ArticleIEEE transactions on automation science and engineering : a publication of the IEEE Robotics and Automation Society2008
A New Approach for Measuring Single-Cell Oxygen Consumption Rates.
Article in IEEE transactions on automation science and engineering : a publication of the IEEE Robotics and Automation Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
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- A physicochemical model of X-ray induced photodynamic therapy (X-PDT) with an emphasis on tissue oxygen concentration and oxygenation.Scientific reports · 2023Article
- Mitochondrial responses to intracellular CaJournal of neurophysiology · 2023Article
- Simultaneous Multiparameter Cellular Energy Metabolism Profiling of Small Populations of Cells.Scientific reports · 2018Article
- A platform for high-throughput bioenergy production phenotype characterization in single cells.Scientific reports · 2017Article
- Microchambers with Solid-State Phosphorescent Sensor for Measuring Single Mitochondrial Respiration.Sensors (Basel, Switzerland) · 2016Article
- Real-time single-cell imaging of protein secretion.Scientific reports · 2014Article
- Oxygen consumption rates of bacteria under nutrient-limited conditions.Applied and environmental microbiology · 2013Article
- Method for physiologic phenotype characterization at the single-cell level in non-interacting and interacting cells.Journal of biomedical optics · 2012Article
- Light-addressable measurements of cellular oxygen consumption rates in microwell arrays based on phase-based phosphorescence lifetime detection.Biomicrofluidics · 2012Article
- Microimaging of oxygen concentration near live photosynthetic cells by electron spin resonance.Biophysical journal · 2010Article
- Microfluidic stochastic confinement enhances analysis of rare cells by isolating cells and creating high density environments for control of diffusible signals.Chemical Society reviews · 2010Review
- Article
- FORMING SELF-ASSEMBLED CELL ARRAYS AND MEASURING THE OXYGEN CONSUMPTION RATE OF A SINGLE LIVE CELL.Digest of technical papers. International Conference on Solid-State Sensors, Actuators, and Microsystems · 2009Article
- A microwell array device capable of measuring single-cell oxygen consumption rates.Sensors and actuators. B, Chemical · 2009Article
- Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability.Angewandte Chemie (International ed. in English) · 2009Article
- A cellular isolation system for real-time single-cell oxygen consumption monitoring.Journal of the Royal Society, Interface · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
A novel system that has enabled the measurement of single-cell oxygen consumption rates is presented. The experimental apparatus includes a temperature controlled environmental chamber, an array of microwells etched in glass, and a lid actuator used to seal cells in the microwells. Each microwell contains an oxygen sensitive platinum phosphor sensor used to monitor the cellular metabolic rates. Custom automation software controls the digital image data collection for oxygen sensor measurements, which are analyzed using an image-processing program to yield the oxygen concentration within each microwell versus time. Two proof-of-concept experiments produced oxygen consumption rate measurements for A549 human epithelial lung cancer cells of 5.39 and 5.27 fmol/min/cell, closely matching published oxygen consumption rates for bulk A549 populations.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.