ArticleApplied and environmental microbiology2011
Stability and tick transmission phenotype of gfp-transformed Anaplasma marginale through a complete in vivo infection cycle.
Article in Applied and environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Recent advances in genetic systems in obligate intracellular human-pathogenic bacteria.Frontiers in cellular and infection microbiology · 2023Review
- Quantitative analysis of Anaplasma marginale acquisition and transmission by Dermacentor andersoni fed in vitro.Scientific reports · 2020Article
- Global Transcription Profiles ofFrontiers in veterinary science · 2020Article
- Peptide Nucleic Acid Knockdown and Intra-host Cell Complementation ofFrontiers in cellular and infection microbiology · 2017Article
- Reduced Infectivity in cattle for an outer membrane protein mutant of Anaplasma marginale.Applied and environmental microbiology · 2015Article
- Understanding Anaplasmataceae pathogenesis using "Omics" approaches.Frontiers in cellular and infection microbiology · 2014Review
- Protective immunity induced by immunization with a live, cultured Anaplasma marginale strain.Vaccine · 2013Article
- Transcriptional pathways associated with the slow growth phenotype of transformed Anaplasma marginale.BMC genomics · 2013Article
- Comparative genomics and transcriptomics of trait-gene association.BMC genomics · 2012Article
- Advances in genetic manipulation of obligate intracellular bacterial pathogens.Frontiers in microbiology · 2011Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
We tested the stability and tick transmission phenotype of transformed Anaplasma marginale through a complete in vivo infection cycle. Similar to the wild type, the gfp-transformed A. marginale strain established infection in cattle, a natural reservoir host, and persisted in immune competent animals. The tick infection rates for the transformed A. marginale and the wild type were the same. However, there were significantly lower levels of the transformed A. marginale than of the wild type in the tick. Despite the lower levels of replication, ticks transmitted the transformant. Transformants can serve as valuable tools to dissect the molecular requirements of tick colonization and pathogen transmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.