ReviewLife sciences2011
Drugs of abuse and HIV infection/replication: implications for mother-fetus transmission.
Review in Life sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- MicroRNAs in HIV infection: dual regulators of viral replication and host immunity.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- The Impact of Drugs and Substance Abuse on Viral Pathogenesis-A South African Perspective.Viruses · 2024Review
- Association between recent methamphetamine use, antiretroviral therapy and HIV viral load; a mediation analysis from a cohort of HIV positive persons who inject drugs in Hai Phong, Vietnam.International journal of STD & AIDS · 2023Article
- Morphine-mediated release of astrocyte-derived extracellular vesicle miR-23a induces loss of pericyte coverage at the blood-brain barrier: Implications for neuroinflammation.Frontiers in cell and developmental biology · 2022Article
- HIV-infection and cocaine use regulate semen extracellular vesicles proteome and miRNAome in a manner that mediates strategic monocyte haptotaxis governed by miR-128 network.Cellular and molecular life sciences : CMLS · 2021Article
- Review
- Lifetime Methamphetamine Use Disorder and Reported Sleep Quality in Adults Living with HIV.AIDS and behavior · 2020Article
- Do Symptoms of Depression Interact with Substance Use to Affect HIV Continuum of Care Outcomes?AIDS and behavior · 2019Article
- Methamphetamine functions as a novel CD4Scientific reports · 2019Article
- Morphine Withdrawal Enhances HIV Infection of Macrophages.Frontiers in immunology · 2019Article
- Oxidative Stress in HIV Infection and Alcohol Use: Role of Redox Signals in Modulation of Lipid Rafts and ATP-Binding Cassette Transporters.Antioxidants & redox signaling · 2018Article
- Drug Use is Associated with Anti-CD4 IgG-mediated CD4+ T Cell Death and Poor CD4+ T Cell Recovery in Viral-suppressive HIV-infected Individuals Under Antiretroviral Therapy.Current HIV research · 2018Article
- Accounting for dropout reason in longitudinal studies with nonignorable dropout.Statistical methods in medical research · 2017Article
- An examination of sex differences in the effects of early-life opiate and alcohol exposure.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Opioids and Viral Infections: A Double-Edged Sword.Frontiers in microbiology · 2016Review
- The Complex Interaction Between Methamphetamine Abuse and HIV-1 Pathogenesis.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2015Review
- Heroin inhibits HIV-restriction miRNAs and enhances HIV infection of macrophages.Frontiers in microbiology · 2015Article
- Impact of cocaine abuse on HIV pathogenesis.Frontiers in microbiology · 2015Review
- Prenatal Alcohol Exposure and the Developing Immune System.Alcohol research : current reviews · 2015Review
- Maternal cocaine use during breastfeeding.Canadian family physician Medecin de famille canadien · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Human immunodeficiency virus (HIV) infection and progression of acquired immunodeficiency syndrome (AIDS) can be modulated by a number of cofactors, including drugs of abuse. Opioids, cocaine, cannabinoids, methamphetamine (METH), alcohol, and other substances of abuse have been implicated as risk factors for HIV infection, as they all have the potential to compromise host immunity and facilitate viral replication. Although epidemiologic evidence regarding the impact of drugs of abuse on HIV disease progression is mixed, in vitro studies as well as studies using in vivo animal models have indicated that drugs of abuse have the ability to enhance HIV infection/replication. Drugs of abuse may also be a risk factor for perinatal transmission of HIV. Because high levels of viral load in maternal blood are associated with increased risk of HIV vertical transmission, it is likely that drugs of abuse play an important role in promoting mother-fetus transmission. Furthermore, because the neonatal immune system differs qualitatively from the adult system, it is possible that maternal exposure to drugs of abuse would exacerbate neonatal immunity defects, facilitating HIV infection of neonate immune cells and promoting HIV vertical transmission. The availability and use of antiretroviral therapy for women infected with HIV increase, there is an increasing interest in determining the impact of drug abuse on efficacy of AIDS Clinical Trials Group (ACTG)-standardized treatment regimens for woman infected with HIV in the context of HIV vertical transmission.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.