ReviewFEBS letters2011
An overview of epigenetics and chemoprevention.
Review in FEBS letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 53 citations in OpenAlex.
- Black raspberries attenuate colonic adenoma development inFood frontiers · 2020Article
- Identification of Caffeic Acid Phenethyl Ester (CAPE) as a Potent Neurodifferentiating Natural Compound That Improves Cognitive and Physiological Functions in Animal Models of Neurodegenerative Diseases.Frontiers in aging neuroscience · 2020Article
- Polyunsaturated fatty acids and DNA methylation in colorectal cancer.World journal of clinical cases · 2019Review
- Modulation of estrogen synthesis and metabolism by phytoestrogensToxicology research · 2017Review
- Cancer cell-specific oligopeptides selected by an integrated microfluidic system from a phage display library for ovarian cancer diagnosis.Theranostics · 2015Article
- Spotlight on decitabine for myelodysplastic syndromes in Chinese patients.OncoTargets and therapy · 2015Review
- Gene methylation profiles as prognostic markers in ovarian clear cell and endometrioid adenocarcinomas.American journal of translational research · 2015Article
- Epigenetic reprogramming of human lung cancer cells with the extract of bovine parthenogenetic oocytes.Journal of cellular and molecular medicine · 2014Article
- DNA methyltransferases: a novel target for prevention and therapy.Frontiers in oncology · 2014Review
- Black raspberries protectively regulate methylation of Wnt pathway genes in precancerous colon tissue.Cancer prevention research (Philadelphia, Pa.) · 2013Article
- Trends in incidence and survival outcome of epithelial ovarian cancer: 30-year national population-based registry in Taiwan.Journal of gynecologic oncology · 2013Article
- Black raspberry-derived anthocyanins demethylate tumor suppressor genes through the inhibition of DNMT1 and DNMT3B in colon cancer cells.Nutrition and cancer · 2013Article
- Environmental toxicants, epigenetics, and cancer.Advances in experimental medicine and biology · 2013Review
- Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells.BMC complementary and alternative medicine · 2012Article
- Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed.Future medicinal chemistry · 2012Review
- Epigenetic mechanisms of pulmonary hypertension.Pulmonary circulationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
It is now appreciated that both genetic alteration, e.g. mutations, and aberrant epigenetic changes, e.g. DNA methylation, cause cancer. Epigenetic dysregulation is potentially reversible which makes it attractive as targets for cancer prevention. Synthetic drugs targeting enzymes, e.g. DNA methyltransferase and histone deacetylase, that regulate epigenetic patterns are active in clinical settings. In addition, dietary factors have been suggested to have potential to reverse aberrant epigenetic patterns. Uncovering the human epigenome can lead us to better understand the dynamics of DNA methylation in disease progression which can further assist in cancer prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.