Evidence map›Paper›PMID 21054333›Full record

ArticleThe British journal of dermatology2011

Lifetime exposure to cigarette smoking and the development of adult-onset atopic dermatitis.

C H Lee, H Y Chuang, C H Hong, S K Huang, Y C Chang, Y C Ko, H S Yu

Abstract read
In one paragraph

Article in The British journal of dermatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Air Pollution and Skin Diseases.Annals of dermatology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Impact of Air Pollution on Atopic Dermatitis: A Comprehensive Review.Clinical reviews in allergy & immunology · 2023
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Aeroallergens in Atopic Dermatitis and Chronic Urticaria.Current allergy and asthma reports · 2022
    Review
  16. Article
  17. Review
  18. Smoking and risk of adult-onset atopic dermatitis in US women.Journal of the American Academy of Dermatology · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

C H LeeDepartment of Dermatology, Kaohsiung Municipal Hsiao-Kang Hospital, Taiwan.
H Y Chuang
C H Hong
S K Huang
Y C Chang
Y C Ko
H S Yu
Center for Environmental Health · USKaohsiung Medical University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWKaohsiung Veterans General Hospital · TW

Funding

Immunogenetic Analysis of Immune Response to AllergensR01AI052468 · NIAID · JOHNS HOPKINS UNIVERSITY · PI HUANG, SHAU-KU · 2003 to 2012
$3.5M
Role of C-type lectin receptors in food allergyR21AI073610 · NIAID · JOHNS HOPKINS UNIVERSITY · PI HUANG, SHAU-KU · 2007 to 2008
$448k
NIAID NIH HHS AI-052468NIAID NIH HHS AI073610NIAID NIH HHS R01 AI052468NIAID NIH HHS R21 AI073610
6 · The paper itself

Abstract

backgroundAdult-onset atopic dermatitis (AD) has recently been recognized as a distinct disease entity, but its risk factors have not yet been clearly defined. Although gestational and perinatal exposure to tobacco smoking may be associated with the development of classic AD, the association between active/passive smoking and adult-onset AD remains controversial.

objectivesTo determine if exposure to smoking, including environmental tobacco smoke (ETS), is associated with the risk of adult-onset AD.

methodsTobacco smoking and exposure to ETS were measured in a case-control association analysis in 83 patients with physician-diagnosed adult-onset AD and 142 age- and sex-matched controls.

resultsMultiple logistic regression analyses showed that, among the potential environmental risk factors, both current and ever smoking were significant risk factors for adult-onset AD [odds ratio (OR) 4·994 and 3·619, respectively], compared with never smoking. Also, packs per year was significantly associated with adult-onset AD (OR 1·058, 95% confidence interval 1·028-1·089), suggesting a lifelong cumulative risk in current smokers. Moreover, nonsmokers with adult-onset AD reported significantly more exposure to ETS.

conclusionsEarly and/or current exposure to cigarette smoking may contribute cumulatively to the development of adult-onset AD. Exposure to ETS in childhood is associated with the development of adult-onset AD. Adults should be discouraged from smoking to prevent adult-onset AD in themselves and their family members.

Indexed as

AdultAgedAge of OnsetCase-Control StudiesCross-Sectional StudiesDermatitis, AtopicFemaleHumansLogistic ModelsMaleMiddle AgedRisk FactorsSmokingSurveys and QuestionnairesTobacco Smoke PollutionTobacco Smoke Pollution

Identifiers

PMID21054333
PMCPMC3062947
OpenAlexW2147668473

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.