ArticleMacromolecules2010
Effective charge and coil-globule transition of a polyelectrolyte chain.
Article in Macromolecules, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Size, Conformation, and Local Domains of Single-Chain Nanoparticles with Intrachain Covalent, Dipolar, and Electrostatic Interactions: Toward Artificial Intrinsically Disordered Proteins.Macromolecules · 2025Article
- Beyond monopole electrostatics in regulating conformations of intrinsically disordered proteins.PNAS nexus · 2024Article
- Driving forces of the complex formation between highly charged disordered proteins.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- FIREBALL: A tool to fit protein phase diagrams based on mean-field theories for polymer solutions.Biophysical journal · 2023Article
- Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Review
- Coexistence of coil and globule domains within a single confined DNA chain.Nucleic acids research · 2016Article
- Theory of volume transition in polyelectrolyte gels with charge regularization.The Journal of chemical physics · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Considering the adsorption of counterions on an isolated polyelectrolyte (PE) chain and using a variational theory, phase boundaries and the critical point for the first-order coil-globule transition are calculated. The transition is induced cooperatively by counterion adsorption and chain conformations and the calculation is done self-consistently. The size of the PE chain is a single-valued function of charge. The discontinuous transition of the coil size is accompanied by a discontinuous transition of the charge. Phase boundaries for the coil-globule transitions induced by both Coulomb strength (inverse temperature or dielectric constant) and ionic strength (salt) show that the PE chain collapses at a substantially lower Coulomb strength in the presence of salt. In the expanded state of the coil, an analytical formula is derived for the effective charge of the chain for conditions where the coupling between chain conformations and counterion adsorption is weak. In general, the dielectric heterogeneity of the solvent close to the polymer backbone is found to play a crucial role in the charge regularization and the chain collapse.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.