Evidence map›Paper›PMID 21051593›Full record

Trial reportPhysical therapy2011

Influence of a locomotor training approach on walking speed and distance in people with chronic spinal cord injury: a randomized clinical trial.

Edelle C Field-Fote, Kathryn E Roach

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physical therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 137 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 17 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03669302 naterminatednot on this mapstarted 2018, after this paper: background citation

Activity-Dependent Transspinal Stimulation for Recovery of Walking Ability After Spinal Cord Injury

TypeinterventionalSponsorCity University of New YorkRan2018 to 2021Enrolled10ConditionsSpinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, SpasticArmsRobotic gait training, Robotic gait training and low-frequency transspinal stimulation, Robotic gait training and high-frequency transspinal stimulation
NCT04052009 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Effects of End-effector Based Training vs. Conventional Gait Training With Incomplete Spinal Cord Injury. A Pilot Study

TypeinterventionalSponsorRehab BaselRan2019 to 2020Enrolled36ConditionsIncomplete Spinal Cord InjuryArmsConventional gait training, End-effector based gait training, combined training (conventional and end-effector-based)
NCT04624607 nacompletednot on this mapstarted 2018, after this paper: background citation

Transspinal-Transcortical Paired Stimulation for Neuroplasticity and Recovery After SCI

TypeinterventionalSponsorCollege of Staten Island, the City University of New YorkRan2018 to 2020Enrolled14ConditionsSpinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/TetraparesisArmsTransspinal-transcortical paired-associative stimiulation combined with robotic gait training, Transcortical-transspinal paired-associative stimiulation combined with robotic gait training
3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 17 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Locomotor training for walking after spinal cord injury.The Cochrane database of systematic reviews · 2012
    Pooled it
  15. Pooled it
  16. Pooled it
  17. Pooled it
  18. Trial
  19. Trial
  20. Trial

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Edelle C Field-FoteDepartment of Physical Therapy, Miller School of Medicine, University of Miami, Miami, Florida, USA. edee@miami.edu
Kathryn E Roach

Funding

Comparison of post-SCI locomotor training techniquesR01HD041487 · NICHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FIELD-FOTE, EDELLE CARMEN · 2002 to 2006
$1.3M
NICHD NIH HHS R01 HD041487NICHD NIH HHS R01HD41487
6 · The paper itself

Abstract

backgroundImpaired walking limits function after spinal cord injury (SCI), but training-related improvements are possible even in people with chronic motor incomplete SCI.

objectiveThe objective of this study was to compare changes in walking speed and distance associated with 4 locomotor training approaches.

designThis study was a single-blind, randomized clinical trial.

settingThis study was conducted in a rehabilitation research laboratory.

participantsParticipants were people with minimal walking function due to chronic SCI.

interventionParticipants (n=74) trained 5 days per week for 12 weeks with the following approaches: treadmill-based training with manual assistance (TM), treadmill-based training with stimulation (TS), overground training with stimulation (OG), and treadmill-based training with robotic assistance (LR). MEASUREMENTS: Overground walking speed and distance were the primary outcome measures.

resultsIn participants who completed the training (n=64), there were overall effects for speed (effect size index [d]=0.33) and distance (d=0.35). For speed, there were no significant between-group differences; however, distance gains were greatest with OG. Effect sizes for speed and distance were largest with OG (d=0.43 and d=0.40, respectively). Effect sizes for speed were the same for TM and TS (d=0.28); there was no effect for LR. The effect size for distance was greater with TS (d=0.16) than with TM or LR, for which there was no effect. Ten participants who improved with training were retested at least 6 months after training; walking speed at this time was slower than that at the conclusion of training but remained faster than before training. LIMITATIONS: It is unknown whether the training dosage and the emphasis on training speed were optimal. Robotic training that requires active participation would likely yield different results.

conclusionsIn people with chronic motor incomplete SCI, walking speed improved with both overground training and treadmill-based training; however, walking distance improved to a greater extent with overground training.

Indexed as

Severity of Illness IndexWalkingAdultChronic DiseaseExercise TestExercise TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedMovement DisordersPhysical Therapy ModalitiesRecovery of FunctionRoboticsSingle-Blind Method

Identifiers

PMID21051593
PMCPMC3017322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.