Evidence map›Paper›PMID 21051346›Full record

ArticleNucleic acids research2011

dbCRID: a database of chromosomal rearrangements in human diseases.

Fanlou Kong, Jing Zhu, Jun Wu, Jianjian Peng, Ying Wang, Qing Wang, Songbin Fu, Li-Lian Yuan, Tongbin Li

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 47 citations in OpenAlex.

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  11. Parp3 promotes long-range end joining in murine cells.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  12. Chimeric RNAs and their implications in cancer.Current opinion in genetics & development · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Fanlou KongBiolead.org Research Group, LC Sciences, Houston, TX 77054, USA.
Jing Zhu
Jun Wu
Jianjian Peng
Ying Wang
Qing Wang
Songbin Fu
Li-Lian Yuan
Tongbin Li
Harbin Medical University · CNUniversity of Minnesota · US

Funding

Proteomic Phosphopeptide Chip Technology for Protein ProfilingR33CA126209 · NCI · UNIVERSITY OF HOUSTON · PI GAO, XIAOLIAN · 2008 to 2010
$1.5M
NCI NIH HHS 5R33 CA126209-03
6 · The paper itself

Abstract

Chromosomal rearrangement (CR) events result from abnormal breaking and rejoining of the DNA molecules, or from crossing-over between repetitive DNA sequences, and they are involved in many tumor and non-tumor diseases. Investigations of disease-associated CR events can not only lead to important discoveries about DNA breakage and repair mechanisms, but also offer important clues about the pathologic causes and the diagnostic/therapeutic targets of these diseases. We have developed a database of Chromosomal Rearrangements In Diseases (dbCRID, http://dbCRID.biolead.org), a comprehensive database of human CR events and their associated diseases. For each reported CR event, dbCRID documents the type of the event, the disease or symptoms associated, and--when possible--detailed information about the CR event including precise breakpoint positions, junction sequences, genes and gene regions disrupted and experimental techniques applied to discover/analyze the CR event. With 2643 records of disease-associated CR events curated from 1172 original studies, dbCRID is a comprehensive and dynamic resource useful for studying DNA breakage and repair mechanisms, and for analyzing the genetic basis of human tumor and non-tumor diseases.

Indexed as

Chromosome AberrationsDatabases, FactualChromosome BreakpointsDiseaseHumansNeoplasmsUser-Computer Interface

Identifiers

PMID21051346
PMCPMC3013658
OpenAlexW2160475182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.