ReviewProtein engineering, design & selection : PEDS2011
Protein folds and protein folding.
Review in Protein engineering, design & selection : PEDS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Three- and four-stranded nucleic acid structures and their ligands.RSC chemical biology · 2025Review
- Folds from fold: Exploring topological isoforms of a single-domain protein.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Protein Fold Usages in Ribosomes: Another Glance to the Past.International journal of molecular sciences · 2024Article
- Fishing for Catalysis: Experimental Approaches to Narrowing Search Space in Directed Evolution of Enzymes.JACS Au · 2023Review
- What's in a Name? An Overview of the Proliferating Nomenclature in the Field of Phage Lysins.Cells · 2023Review
- Structural screens identify candidate human homologs of insect chemoreceptors and crypticeLife · 2023Article
- Binding and Functional Folding (BFF): A Physiological Framework for Studying Biomolecular Interactions and Allostery.Journal of molecular biology · 2022Review
- Metal-Specificity Divergence between Metallothioneins ofInternational journal of molecular sciences · 2021Article
- FoldHSphere: deep hyperspherical embeddings for protein fold recognition.BMC bioinformatics · 2021Article
- Open-access data: A cornerstone for artificial intelligence approaches to protein structure prediction.Structure (London, England : 1993) · 2021Review
- Tumorigenic p53 mutants undergo common structural disruptions including conversion to α-sheet structure.Protein science : a publication of the Protein Society · 2020Article
- Classification and Computational Analysis ofFrontiers in genetics · 2020Article
- Functional Evolution of Proteins.Proteins · 2019Article
- The Role of Hydrogen Bonding in the Folding/Unfolding Process of Hydrated Lysozyme: A Review of Recent NMR and FTIR Results.International journal of molecular sciences · 2018Review
- Role of single-point mutations and deletions on transition temperatures in ideal proteinogenic heteropolymer chains in the gas phase.European biophysics journal : EBJ · 2016Article
- New Dynamic Rotamer Libraries: Data-Driven Analysis of Side-Chain Conformational Propensities.Structure (London, England : 1993) · 2016Article
- Energetic frustrations in protein folding at residue resolution: a homologous simulation study of Im9 proteins.PloS one · 2014Article
- Conservation of protein structure over four billion years.Structure (London, England : 1993) · 2013Article
- When a domain is not a domain, and why it is important to properly filter proteins in databases: conflicting definitions and fold classification systems for structural domains make filtering of such databases imperative.BioEssays : news and reviews in molecular, cellular and developmental biology · 2012Article
- Independent structural domains in paramyxovirus polymerase protein.The Journal of biological chemistry · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The classification of protein folds is necessarily based on the structural elements that distinguish domains. Classification of protein domains consists of two problems: the partition of structures into domains and the classification of domains into sets of similar structures (or folds). Although similar topologies may arise by convergent evolution, the similarity of their respective folding pathways is unknown. The discovery and the characterization of the majority of protein folds will be followed by a similar enumeration of available protein folding pathways. Consequently, understanding the intricacies of structural domains is necessary to understanding their collective folding pathways. We review the current state of the art in the field of protein domain classification and discuss methods for the systematic and comprehensive study of protein folding across protein fold space via atomistic molecular dynamics simulation. Finally, we discuss our large-scale Dynameomics project, which includes simulations of representatives of all autonomous protein folds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.