Trial reportThe Journal of allergy and clinical immunology2010
Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program.
Trial report in The Journal of allergy and clinical immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 45 citations in OpenAlex.
- Group-randomized trial of tailored brief shared decision-making to improve asthma control in urban black adults.Journal of advanced nursing · 2021Trial
- Impact of race on asthma treatment failures in the asthma clinical research network.American journal of respiratory and critical care medicine · 2011Trial
- Race Adjusted for Social and Environmental Disparities Is the Principal Determinant of T2HIGH Inflammation in Children With Severe Asthma.The journal of allergy and clinical immunology. In practice · 2026Article
- Racial Differences in Patterns of Long-Term Conditions Among Adults With Asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Article
- Assessing the feasibility of indoor air quality monitoring in low-income housing among Black adults with uncontrolled asthma in New York City.BMC public health · 2026Article
- Environmental justice and allergic disease: A Work Group Report of the AAAAI Environmental Exposure and Respiratory Health Committee and the Diversity, Equity and Inclusion Committee.The Journal of allergy and clinical immunology · 2023Article
- Historical Redlining Impacts Contemporary Environmental and Asthma-related Outcomes in Black Adults.American journal of respiratory and critical care medicine · 2022Article
- Speech recognition can help evaluate shared decision making and predict medication adherence in primary care setting.PloS one · 2022Article
- An Overview of Health Disparities in Asthma.The Yale journal of biology and medicine · 2021Review
- Unsupervised modeling and genome-wide association identify novel features of allergic march trajectories.The Journal of allergy and clinical immunology · 2021Article
- Seeing the Window, Finding the Spider: Applying Critical Race Theory to Medical Education to Make Up Where Biomedical Models and Social Determinants of Health Curricula Fall Short.Frontiers in public health · 2021Article
- Asthma severity in four countries of Latin America.BMC pulmonary medicine · 2019Article
- Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.The Journal of allergy and clinical immunology · 2019Article
- African ancestry is associated with cluster-based childhood asthma subphenotypes.BMC medical genomics · 2018Article
- Predictors of emergency department use in children with persistent asthma in metropolitan Atlanta, Georgia.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017Article
- Resolving the etiology of atopic disorders by using genetic analysis of racial ancestry.The Journal of allergy and clinical immunology · 2016Review
- Obesity, low levels of physical activity and smoking present opportunities for primary care asthma interventions: an analysis of baseline data from The Asthma Tools Study.NPJ primary care respiratory medicine · 2015Article
- Time Trends in Racial and Ethnic Disparities in Asthma Prevalence in the United States From the Behavioral Risk Factor Surveillance System (BRFSS) Study (1999-2011).American journal of public health · 2015Article
- Age at cancer diagnosis for blacks compared with whites in the United States.Journal of the National Cancer Institute · 2015Article
- Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study.The Journal of allergy and clinical immunology · 2012Article
Corrections and comments
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Authors and funding
14 authors at 10 institutions in 2 countries.
Funding
Abstract
backgroundBiologic factors are known to contribute to asthma severity. It is unknown whether these factors differentially contribute to asthma severity in black compared with white subjects.
objectiveWe sought to assess the extent to which racial disparities between black and white subjects with severe asthma are attributable to physiologic, immunoinflammatory, and sociodemographic variables.
methodsBlack and white asthmatic adults enrolled in a cross-sectional study focused on severe asthma were evaluated. Severe asthma was identified by using the American Thoracic Society definition. After initial univariable analyses, unconditional logistic regression models were used to estimate the probability of having severe asthma for black and white subjects.
resultsDifferences in severe asthma in black compared with white subjects were observed. In univariable analysis IgE level was not associated with severe asthma in black or white subjects, whereas in multivariable analysis IgE level was significantly associated with severe asthma for black subjects (P = .014) but not for white subjects. The odds of having severe asthma more than doubled for black subjects with 2 or more family members with asthma (P = .026), whereas the odds of severe asthma for white participants with a strong family history of asthma decreased by almost half (P = .05). Atopy was negatively associated with severe asthma in both races in univariable analysis but remained significant only in black subjects, whereas comorbidities were associated with severe asthma in white subjects.
conclusionBiologic factors were distinctly associated with severe asthma only in black subjects. Studies that incorporate comprehensive evaluation of biologic factors associated with asthma might lead to the development of therapies that target biologic abnormalities in black subjects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.