SynthesisThe Lancet. Infectious diseases2010
Priorities for tuberculosis research: a systematic review.
Synthesis in The Lancet. Infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- How are health research priorities set in low and middle income countries? A systematic review of published reports.PloS one · 2014Pooled it
- Pooled it
- Subnational burden estimates to find missing people with tuberculosis: wrong but useful?BMC global and public health · 2024Review
- Association between fatty acid metabolism gene mutations and Mycobacterium tuberculosis transmission revealed by whole genome sequencing.BMC microbiology · 2023Article
- The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach.PloS one · 2023Article
- Lack of systematicity in research prioritisation processes - a scoping review of evidence syntheses.Systematic reviews · 2022Article
- Methods for Identifying Health Research Gaps, Needs, and Priorities: a Scoping Review.Journal of general internal medicine · 2022Article
- What do we know about evidence-informed priority setting processes to set population-level health-research agendas: an overview of reviews.Bulletin of the National Research Centre · 2022Review
- Involving stakeholders in research priority setting: a scoping review.Research involvement and engagement · 2021Article
- Reporting guideline for priority setting of health research (REPRISE).BMC medical research methodology · 2019Article
- Treatment of Drug-Resistant Tuberculosis.Clinics in chest medicine · 2019Review
- Scoping review of priority setting of research topics for musculoskeletal conditions.BMJ open · 2018Article
- Classification and reporting of severity experienced by animals used in scientific procedures: FELASA/ECLAM/ESLAV Working Group report.Laboratory animals · 2018Article
- Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis.PloS one · 2018Article
- Review
- Setting priorities for a research agenda to combat drug-resistant tuberculosis in children.Public health action · 2015Article
- Host Protein Biomarkers Identify Active Tuberculosis in HIV Uninfected and Co-infected Individuals.EBioMedicine · 2015Article
- In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA.Memorias do Instituto Oswaldo Cruz · 2014Article
- An exploration of NHS staff views on tuberculosis service delivery in Scottish NHS boards.Journal of infection prevention · 2014Article
- Prognostic value of a quantitative analysis of lipoarabinomannan in urine from patients with HIV-associated tuberculosis.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Reliable and relevant research can help to improve tuberculosis control worldwide. In recent years, various organisations have assessed research needs and proposed priorities for tuberculosis. We summarise existing priority statements and assess the rigour of the methods used to generate them. We found 33 documents that specifically outline priorities in tuberculosis research. The top priority areas were drug development (28 articles), diagnosis and diagnostic tests (27), epidemiology (20), health services research (16), basic research (13), and vaccine development and use (13). The most focused questions were on the treatment and prevention of multidrug-resistant tuberculosis in people co-infected with HIV. Methods used to identify these priorities were varied. Improvements can be made to ensure the process is more rigorous and transparent, and to use existing research or systematic reviews more often. WHO, Stop TB Partnership, and other organisations could adopt an incremental process of priority development, building on the existing knowledge base.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.