ArticlePatient preference and adherence2010
Varenicline for smoking cessation: efficacy, safety, and treatment recommendations.
Article in Patient preference and adherence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02378714 (Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers), which is not on this map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Who cites it
30 citing papers in PubMed, 69 citations in OpenAlex.
- Timing of smoking cessation treatment integrated into outpatient treatment with medications for opioid use disorder: Feasibility trial.Journal of substance abuse treatment · 2022Trial
- Impact of early nausea on varenicline adherence and smoking cessation.Addiction (Abingdon, England) · 2020Trial
- Determinants of Repetitive Transcranial Magnetic Stimulation Efficacy in Tobacco Use Disorder: A Pre-Registered Study.medRxiv : the preprint server for health sciences · 2026Article
- Contemporary preoperative assessment for colorectal surgery: new insights and developments.BMJ open gastroenterology · 2026Review
- Genome-Wide Association Study of Varenicline-Aided Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Cytisinicline vs. Varenicline in Tobacco Addiction: A Literature Review Focused on Emotional Regulation, Psychological Symptoms, and Mental Health.Healthcare (Basel, Switzerland) · 2025Review
- E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis.AJPM focus · 2025Article
- Article
- Individual variations in motives for nicotine self-administration in male rats: evidence in support for a precision psychopharmacology.Translational psychiatry · 2024Article
- Identification of nicotine-seeking and avoiding larval zebrafish using a new three-choice behavioral assay.Frontiers in molecular neuroscience · 2023Article
- Stability of Varenicline Concentration in Saliva Over 21 Days at Three Storage Temperatures.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Article
- The role of nicotinic acetylcholine receptors in alcohol-related behaviors.Brain research bulletin · 2020Review
- Role of corticotropin-releasing factor in alcohol and nicotine addiction.Brain research · 2020Review
- The effect of a multidisciplinary approach for smoking cessation in patients with Crohn's disease: Results from an observational cohort study.Tobacco induced diseases · 2020Article
- E-cigarette Usage Is Associated With Increased Past-12-Month Quit Attempts and Successful Smoking Cessation in Two US Population-Based Surveys.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Comparison of Various Chromatographic Systems for Analysis of Cytisine in Human Serum, Saliva and Pharmaceutical Formulation by HPLC with Diode Array, Fluorescence or Mass Spectrometry Detection.Molecules (Basel, Switzerland) · 2019Article
- Fit & quit: An efficacy trial of two behavioral post-cessation weight gain interventions.Contemporary clinical trials · 2019Article
- Varenicline Targets the Reinforcing-Enhancing Effect of Nicotine on Its Associated Salient Cue During Nicotine Self-administration in the Rat.Frontiers in behavioral neuroscience · 2019Article
- Measures and predictors of varenicline adherence in the treatment of nicotine dependence.Addictive behaviors · 2017Article
- Trends in utilization of smoking cessation agents before and after the passage of FDA boxed warning in the United States.Drug and alcohol dependence · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a public health priority. Patients achieve the greatest success when quit attempts involve behavioral therapy combined with pharmacotherapy. Varenicline is the most recent addition to the pharmacotherapeutic armamentarium for the treatment of tobacco dependence. Varenicline is efficacious and cost-effective. Smoking relapse and adverse treatment-related side effects may decrease medication adherence and patient satisfaction with varenicline. In the clinical setting, varenicline treatment can be optimized by reducing doses in patients who experience intolerable side effects, increasing the dose in partial responders, and providing long-term maintenance therapy for relapse prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.