Evidence map›Paper›PMID 21048758›Full record

ArticleNature2010

Structural biology: On stress and pressure.

Curt D Sigmund

Abstract readNewsComment
PubMed Publisher
In one paragraph

Article in Nature, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Angiotensin II blockade and renal protection.Current pharmaceutical design · 2013
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Curt D Sigmund

Funding

VASOPRESSIN IN CARDIOVASCULAR REGULATIONP01HL014388 · NHLBI · UNIVERSITY OF IOWA · PI ABBOUD, FRANCOIS M · 1985 to 2018
$40.3M
Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI GROBE, JUSTIN L · 2007 to 2022
$30.2M
SIGNIFICANCE OF ANGIOTENSINOGEN VARIANTS IN HYPERTENSIONR01HL061446 · NHLBI · UNIVERSITY OF IOWA · PI SIGMUND, CURT DANIEL · 1999 to 2013
$4.8M
Role of Enhancers Regulating Renin Gene ExpressionR37HL048058 · NHLBI · UNIVERSITY OF IOWA · PI SIGMUND, CURT DANIEL · 2006 to 2015
$4.3M
NHLBI NIH HHS P01 HL014388NHLBI NIH HHS P01 HL084207NHLBI NIH HHS R01 HL061446NHLBI NIH HHS R37 HL048058
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AngiotensinogenAngiotensinsAnimalsBlood PressureCrystallography, X-RayFemaleHumansMiceOxidation-ReductionOxidative StressPregnancyProtein ConformationProtein Processing, Post-TranslationalRatsReactive Oxygen SpeciesReninAngiotensinogenAngiotensinsReactive Oxygen SpeciesReninSuperoxides

Identifiers

PMID21048758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.