Evidence map›Paper›PMID 21048526›Full record

ArticlePharmacogenetics and genomics2011

Doxorubicin pathways: pharmacodynamics and adverse effects.

Caroline F Thorn, Connie Oshiro, Sharon Marsh, Tina Hernandez-Boussard, Howard McLeod, Teri E Klein, Russ B Altman

Abstract read
In one paragraph

Article in Pharmacogenetics and genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 702 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
702citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

702 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. The gut-heart axis in cardio-oncology.Cardiovascular research · 2026
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Article

642 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caroline F ThornDepartments of Genetics, Stanford University Medical Center, California 94305-5120, USA.
Connie Oshiro
Sharon Marsh
Tina Hernandez-Boussard
Howard McLeod
Teri E Klein
Russ B Altman

Funding

THE STANFORD PHARMACOGENETICS KNOWLEDGE BASEU01GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO · 2000 to 2009
$24.0M
NIGMS NIH HHS U01 GM061374NIGMS NIH HHS U01GM61374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibiotics, AntineoplasticDoxorubicinDrug Resistance, NeoplasmHumansIntercalating AgentsPharmacogeneticsPhenotypePolymorphism, GeneticAntibiotics, AntineoplasticDoxorubicinIntercalating Agents

Identifiers

PMID21048526
PMCPMC3116111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.