Evidence map›Paper›PMID 21048428›Full record

ArticleCell adhesion & migration

Extracellular matrix-derived peptides and myocardial repair.

Shirley S Mihardja, Jiashing Yu, Randall J Lee

Open access · goldAbstract read
In one paragraph

Article in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shirley S MihardjaCardiovascular Research Institute, University of California-San Francisco, CA, USA.
Jiashing Yu
Randall J Lee
Cardiovascular Institute Hospital · JPUniversity of San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repairing cardiac tissue remains one of the most challenging goals in tissue engineering. Here, we discuss ways whereby we sought to treat myocardial infarctions using extracellular-matrix derived peptides. Using an ischemia/reperfusion myocardial infarction rodent model, we targeted these extracellular matrix-derived peptides to the myocardial infarct site and were able to induce angiogenesis and alter the negative remodeling seen after an acute myocardial infarction. Our results indicate a potentially new strategy for repairing damaged tissue.

Indexed as

Angiogenesis Inducing AgentsAnimalsAntibodiesDisease Models, AnimalExtracellular MatrixExtracellular Matrix ProteinsImmunoconjugatesMyocardial InfarctionMyocardiumPeptidesRatsReperfusion InjuryTissue EngineeringVentricular RemodelingAngiogenesis Inducing AgentsAntibodiesExtracellular Matrix ProteinsImmunoconjugatesPeptides

Identifiers

PMID21048428
PMCPMC3084975
OpenAlexW1990697032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.