Evidence map›Paper›PMID 21046124›Full record

ArticleEuropean journal of nutrition2011

Whey protein precludes lipid and protein oxidation and improves body weight gain in resistance-exercised rats.

Fabiano Kenji Haraguchi, Marcelo Eustáquio Silva, Leandro Xavier Neves, Rinaldo Cardoso dos Santos, Maria Lúcia Pedrosa

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Article in European journal of nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

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  10. Effects of Whey Powder Supplementation on Dry-Aged Meat Quality.Korean journal for food science of animal resources · 2016
    Article
  11. Antioxidant Effects of Sheep Whey Protein on Endothelial Cells.Oxidative medicine and cellular longevity · 2016
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fabiano Kenji HaraguchiResearch in Biological Sciences-NUPEB, Ouro Preto University, Minas Gerais, Brazil. fabianokenji@gmail.com
Marcelo Eustáquio Silva
Leandro Xavier Neves
Rinaldo Cardoso dos Santos
Maria Lúcia Pedrosa
Universidade Federal de Ouro Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResistance exercise such as weight-lifting (WL) increases oxidation products in plasma, but less is known regarding the effect of WL on oxidative damage to tissues. Dietary compounds are known to improve antioxidant defences. Whey protein (WP) is a source of protein in a variety of sport supplements and can enhance physical performance.

aimTo evaluate the effect of WL on biomarkers of lipid and protein oxidation, on liver antioxidants and on muscle growth in the absence or presence of WP in rats.

methodsThirty-two male Fisher rats were randomly assigned to sedentary or exercise-trained groups and were fed with control or WP diets. The WL programme consisted of inducing the animals to perform sets of jumps with weights attached to the chest. After 8 weeks, arteriovenous blood samples, abdominal fat, liver and gastrocnemius muscle were collected for analysis.

resultsWP precludes WL-mediated increases in muscle protein carbonyl content and maintains low levels of TBARS in exercised and sedentary animals. WL reduced liver CAT activity, whereas WP increased hepatic glutathione content. In addition, WL plus WP generated higher body and muscle weight than exercise without WP.

conclusionsThese data suggest that WP improves antioxidant defences, which contribute to the reduction of lipid and protein oxidation as well as body and muscle weight gain in resistance-exercised rats.

Indexed as

Lipid MetabolismPhysical Conditioning, AnimalAbdominal FatAnimalsAntioxidantsBiomarkersBody WeightCatalaseDietGlutathioneGlycogenLiverMaleMilk ProteinsMuscle, SkeletalOxidation-ReductionAntioxidantsBiomarkersCatalaseGlutathioneGlycogenMilk ProteinsThiobarbituric Acid Reactive SubstancesWhey Proteins

Identifiers

PMID21046124
OpenAlexW2051577461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.