ArticleJournal of acquired immune deficiency syndromes (1999)2010
Infectious disease comorbidities adversely affecting substance users with HIV: hepatitis C and tuberculosis.
Article in Journal of acquired immune deficiency syndromes (1999), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Harm reduction program and hepatitis C prevalence in people who inject drugs (PWID) in Iran: an updated systematic review and cumulative meta-analysis.Harm reduction journal · 2021Pooled it
- High hepatitis C virus prevalence among drug users in Iran: systematic review and meta-analysis of epidemiological evidence (2001-2012).International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2015Pooled it
- Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an International Association of Physicians in AIDS Care panel.Annals of internal medicine · 2012Guideline
- A rapid ethnographic study of risk negotiation during the COVID-19 pandemic among unstably housed people who use drugs in Rhode Island.The International journal on drug policy · 2022Article
- Ingenuity and resiliency of syringe service programs on the front lines of the opioid overdose and COVID-19 crises.Translational research : the journal of laboratory and clinical medicine · 2021Article
- Challenges posed by COVID-19 to people who inject drugs and lessons from other outbreaks.Journal of the International AIDS Society · 2020Article
- Prevalence of hepatitis C virus and human immunodeficiency virus in a group of patients newly diagnosed with active tuberculosis in Porto Alegre, Southern Brazil.Memorias do Instituto Oswaldo Cruz · 2017Article
- Article
- Challenges in managing HIV in people who use drugs.Current opinion in infectious diseases · 2015Review
- Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA.Epidemiology and infection · 2014Article
- Tuberculosis screening in a novel substance abuse treatment center in Malaysia: implications for a comprehensive approach for integrated care.Journal of substance abuse treatment · 2014Article
- Utilizing buprenorphine-naloxone to treat illicit and prescription-opioid dependence.Neuropsychiatric disease and treatment · 2014Review
- Hepatitis C treatment access and uptake for people who inject drugs: a review mapping the role of social factors.Harm reduction journal · 2013Review
- Coexisting social conditions and health problems among clients seeking treatment for illicit drug use in Finland: the HUUTI study.BMC public health · 2013Article
- Rifampin, but not rifabutin, may produce opiate withdrawal in buprenorphine-maintained patients.Drug and alcohol dependence · 2011Article
- Improving public health through access to and utilization of medication assisted treatment.International journal of environmental research and public health · 2011Review
- Enhanced tuberculosis case detection among substitution treatment patients: a randomized controlled trial.BMC research notes · 2011Article
- Prevention and treatment of HIV/AIDS among drug-using populations: a global perspective.Journal of acquired immune deficiency syndromes (1999) · 2010Article
- Hematological particularities and co-infections in injected drug users with AIDS.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The linkage between drug use, particularly injection drug use, and HIV/AIDS, hepatitis C (HCV), and tuberculosis (TB) has been recognized since the beginning of the HIV pandemic. These comorbid conditions affect drug users worldwide and act synergistically, with resultant adverse biologic, epidemiologic, and clinical consequences. Prevention, care, and treatment of TB and HCV can be successful, and both diseases can be cured. Special clinical challenges among drug users, however, can result in increased morbidity, mortality, and decreased therapeutic success. Among these are limited disease screening, inadequate and insensitive diagnostics, difficult treatment regimens with varying toxicities, and complicated pharmacokinetic and pharmacodynamic drug interactions. These may result in delayed diagnosis, deferred treatment initiation, and low completion rates, with the potential for generation and transmission of drug resistant organisms. Strategies to address these challenges include outreach programs to engage substance abusers in nonmedical settings, such as prisons and the streets, active screening programs for HIV, HCV, and TB, increased and broadened clinician expertise, knowledge and avoidance of drug interactions, attention to infection control, use of isoniazid preventive therapy, and creative strategies to insure medication adherence. All of these require structural changes directed at comprehensive prevention and treatment programs and increased collaboration and integration of needed services for substance abusers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.