ReviewJournal of acquired immune deficiency syndromes (1999)2010
Drug treatment as HIV prevention: a research update.
Review in Journal of acquired immune deficiency syndromes (1999), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 1 synthesis or guideline pooled it.
- HIV infection and risk of overdose: a systematic review and meta-analysis.AIDS (London, England) · 2012Pooled it
- Constructing Taxonomies: Identifying Distinctive Class of HIV Support and Risk Networks among People Who Use Drugs (PWID) and Their Network Members in the HPTN 037 Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Cocaine-using substance abuse treatment patients with and without HIV respond well to contingency management treatment.Journal of substance abuse treatment · 2017Trial
- Expanding substance use treatment options for HIV prevention with buprenorphine-naloxone: HIV Prevention Trials Network 058.Journal of acquired immune deficiency syndromes (1999) · 2015Trial
- Extended release naltrexone injection is performed in the majority of opioid dependent patients receiving outpatient induction: a very low dose naltrexone and buprenorphine open label trial.Drug and alcohol dependence · 2014Trial
- Cost-effectiveness of buprenorphine and naltrexone treatments for heroin dependence in Malaysia.PloS one · 2012Trial
- Trial
- Delivering HIV-Positive Test Results via Phone: Who Never Answered? Correlates of Undelivered Reactive HIV Results in a U.S. National Cohort of Sexual and Gender Minority Individuals.AIDS and behavior · 2026Article
- Digital Interventions for Stimulant Use Among People Living with HIV: A Narrative Review.Current HIV/AIDS reports · 2025Review
- Past-Year HIV Testing, Current Antiretroviral Therapy Use, and Participation in Services for People Who Inject Drugs.AIDS and behavior · 2024Article
- Willingness to utilize a mobile treatment unit in five counties at the epicenter of the US rural opioid epidemic.Journal of substance use and addiction treatment · 2024Article
- Evaluating the agreement between different substance use recall periods in multiple HIV cohorts.Drug and alcohol dependence · 2024Article
- Person-time spent with HIV viral load above 1500 copies/mL among Miami-Dade County Ryan White Program clients, 2017-2019: a retrospective analysis.Annals of epidemiology · 2023Article
- Cessation of self-reported opioid use and impacts on co-occurring health conditions.Drug and alcohol dependence · 2023Article
- Polydrug Use, Sexual Risk, and HIV Testing Among Cisgender Gay, Bisexual, and Other Men and Transgender and Nonbinary Individuals Who Have Sex With Men in Kazakhstan.AIDS education and prevention : official publication of the International Society for AIDS Education · 2022Article
- Stimulant use interventions may strengthen 'Getting to Zero' HIV elimination initiatives in Illinois: Insights from a modeling study.The International journal on drug policy · 2022Article
- Opioid use disorder: a neglected human immunodeficiency virus risk in American adolescents.AIDS (London, England) · 2021Article
- COVID-19 and People Who Use Drugs - A Commentary.Health behavior and policy review · 2020Article
- Rapid Implementation of Service Delivery Changes to Mitigate COVID-19 and Maintain Access to Methadone Among Persons with and at High-Risk for HIV in an Opioid Treatment Program.AIDS and behavior · 2020Article
- Preventing transitions into injection drug use: A call for gender-responsive upstream prevention.The International journal on drug policy · 2020Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Drug use continues to be a major factor fueling the global epidemic of HIV infection. This article reviews the current literature on the ability of drug treatment programs to reduce HIV transmission among injection and noninjection drug users. Most data come from research on the treatment of opiate dependence and provide strong evidence on the effectiveness of medication-assisted treatment for reducing the frequency of drug use, risk behaviors, and HIV infections. This has been a consistent finding since the epidemic began among diverse populations and cultural settings. Use of medications other than methadone (such as buprenorphine/naloxone and naltrexone) has increased in recent years with promising data on their effectiveness as HIV prevention and as new treatment options for communities heavily affected by opiate use and HIV infection. However, few treatment interventions for stimulant abuse and dependence have shown efficacy in reducing HIV risk. The cumulative literature provides strong support of drug treatment programs for improving access and adherence to antiretroviral treatment. Drug users in substance abuse treatment are significantly more likely to achieve sustained viral suppression, making viral transmission less likely. Although there are challenges to implementing drug treatment programs for maximum impact, the scientific literature leaves no doubt about the effectiveness of drug treatment as an HIV prevention strategy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.