Evidence map›Paper›PMID 21045541›Full record

ReviewRNA biology

RNA folding in living cells.

Georgeta Zemora, Christina Waldsich

Abstract readReview
In one paragraph

Review in RNA biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. RNAloops: a database of RNA multiloops.Bioinformatics (Oxford, England) · 2022
    Article
  6. Review
  7. Predicting RNA Secondary Structure Using In Vitro and In Vivo Data.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  8. Review
  9. Transcription Regulation Through Nascent RNA Folding.Journal of molecular biology · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Computational Methods for Modeling Aptamers and Designing Riboswitches.International journal of molecular sciences · 2017
    Review
  14. Understanding the kinetic mechanism of RNA single base pair formation.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Georgeta ZemoraDepartment of Biochemistry and Cell Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.
Christina Waldsich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA folding is the most essential process underlying RNA function. While significant progress has been made in understanding the forces driving RNA folding in vitro, exploring the rules governing intracellular RNA structure formation is still in its infancy. The cellular environment hosts a great diversity of factors that potentially influence RNA folding in vivo. For example, the nature of transcription and translation is known to shape the folding landscape of RNA molecules. Trans-acting factors such as proteins, RNAs and metabolites, among others, are also able to modulate the structure and thus the fate of an RNA. Here we summarize the ongoing efforts to uncover how RNA folds in living cells.

Indexed as

Nucleic Acid ConformationIntracellular SpaceKineticsMolecular ChaperonesProtein BindingRNARNA HelicasesRNA, UntranslatedThermodynamicsTranscription, GeneticMolecular ChaperonesRNARNA HelicasesRNA, Untranslated

Identifiers

PMID21045541
PMCPMC3073324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.