ReviewMicrocirculation (New York, N.Y. : 1994)2010
Spatial and temporal coordination of bone marrow-derived cell activity during arteriogenesis: regulation of the endogenous response and therapeutic implications.
Review in Microcirculation (New York, N.Y. : 1994), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 52 citations in OpenAlex.
- Article
- Lipocalin 2 deficiency impacts angiogenesis after ischemia in vivo and in vitro.Vascular biology (Bristol, England) · 2025Article
- Deletion of the aryl hydrocarbon receptor in endothelial cells improves ischemic angiogenesis in chronic kidney disease.American journal of physiology. Heart and circulatory physiology · 2024Article
- Diabetes mellitus in peripheral artery disease: Beyond a risk factor.Frontiers in cardiovascular medicine · 2023Review
- Neutrophil dynamics and inflammaging in acute ischemic stroke: A transcriptomic review.Frontiers in aging neuroscience · 2022Review
- Visceral fat index: a novel predictor for coronary collateral circulation.Archives of endocrinology and metabolism · 2020Article
- In vivo imaging of hemodynamic redistribution and arteriogenesis across microvascular network.Microcirculation (New York, N.Y. : 1994) · 2020Article
- Epigenetic regulators of the revascularization response to chronic arterial occlusion.Cardiovascular research · 2019Review
- Exposure of Endothelium to Biomimetic Flow Waveforms Yields Identification of miR-199a-5p as a Potent Regulator of Arteriogenesis.Molecular therapy. Nucleic acids · 2018Article
- Cellular and Molecular Heterogeneity Associated with Vessel Formation Processes.BioMed research international · 2018Review
- MicroRNA-146a Regulates Perfusion Recovery in Response to Arterial OcclusionFrontiers in bioengineering and biotechnology · 2018Article
- Temporal remodeling of pial collaterals and functional deficits in a murine model of ischemic stroke.Journal of neuroscience methods · 2018Article
- DNA Methyltransferase 1-Dependent DNA Hypermethylation Constrains Arteriogenesis by Augmenting Shear Stress Set Point.Journal of the American Heart Association · 2017Article
- Arteriogenesis in murine adipose tissue is contingent on CD68Microcirculation (New York, N.Y. : 1994) · 2017Article
- CCR7-CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia.Journal of the American Heart Association · 2017Article
- Optical coherence tomography based microangiography provides an ability to longitudinally image arteriogenesis in vivo.Journal of neuroscience methods · 2016Article
- Vascular growth responses to chronic arterial occlusion are unaffected by myeloid specific focal adhesion kinase (FAK) deletion.Scientific reports · 2016Article
- Macrophage Recruitment and Polarization During Collateral Vessel Remodeling in Murine Adipose Tissue.Microcirculation (New York, N.Y. : 1994) · 2016Article
- Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Reversed Flow Direction.Arteriosclerosis, thrombosis, and vascular biology · 2015Article
- Collaterals: Implications in cerebral ischemic diseases and therapeutic interventions.Brain research · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Arterial occlusive disease is the leading cause of morbidity and mortality throughout the developed world, which creates a significant need for effective therapies to halt disease progression. Despite success of animal and small-scale human therapeutic arteriogenesis studies, this promising concept for treating arterial occlusive disease has yielded largely disappointing results in large-scale clinical trials. One reason for this lack of successful translation is that endogenous arteriogenesis is highly dependent on a poorly understood sequence of events and interactions between bone marrow derived cells (BMCs) and vascular cells, which makes designing effective therapies difficult. We contend that the process follows a complex, ordered sequence of events with multiple, specific BMC populations recruited at specific times and locations. Here, we present the evidence suggesting roles for multiple BMC populations-from neutrophils and mast cells to progenitor cells-and propose how and where these cell populations fit within the sequence of events during arteriogenesis. Disruptions in these various BMC populations can impair the arteriogenesis process in patterns that characterize specific patient populations. We propose that an improved understanding of how arteriogenesis functions as a system can reveal individual BMC populations and functions that can be targeted for overcoming particular impairments in collateral vessel development.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.