Evidence map›Paper›PMID 21042924›Full record

GuidelineEuropean child & adolescent psychiatry2011

European guidelines on managing adverse effects of medication for ADHD.

J Graham, T Banaschewski, J Buitelaar, D Coghill, M Danckaerts, R W Dittmann, M Döpfner, R Hamilton, C Hollis, M Holtmann and 13 more

Abstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in European child & adolescent psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

J GrahamChild and Adolescent Psychiatry, The Centre for Child Health, Dundee, UK. JGraham3@nhs.net
T Banaschewski
J Buitelaar
D Coghill
M Danckaerts
R W Dittmann
M Döpfner
R Hamilton
C Hollis
M Holtmann
M Hulpke-Wette
M Lecendreux
E Rosenthal
A Rothenberger
P Santosh
J Sergeant
E Simonoff
E Sonuga-Barke
I C K Wong
A Zuddas
H-C Steinhausen
E Taylor
European Guidelines Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The safety of ADHD medications is not fully known. Concerns have arisen about both a lack of contemporary-standard information about medications first licensed several decades ago, and signals of possible harm arising from more recently developed medications. These relate to both relatively minor adverse effects and extremely serious issues such as sudden cardiac death and suicidality. A guidelines group of the European Network for Hyperkinetic Disorders (EUNETHYDIS) has therefore reviewed the literature, recruited renowned clinical subspecialists and consulted as a group to examine these concerns. Some of the effects examined appeared to be minimal in impact or difficult to distinguish from risk to untreated populations. However, several areas require further study to allow a more precise understanding of these risks.

Indexed as

Monitoring, PhysiologicAdrenergic Uptake InhibitorsAtomoxetine HydrochlorideAttention Deficit Disorder with HyperactivityCardiovascular DiseasesCentral Nervous System StimulantsChildClinical Trials as TopicDrug Administration ScheduleDrug Dosage CalculationsDrug ToleranceDrug Utilization ReviewEuropeHumansPropylaminesRisk AssessmentAdrenergic Uptake InhibitorsAtomoxetine HydrochlorideCentral Nervous System StimulantsPropylamines

Identifiers

PMID21042924
PMCPMC3012210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.