Evidence map›Paper›PMID 21042880›Full record

ArticleNeurocritical care2011

Abnormal neuroimaging is associated with early in-hospital seizures in pediatric abusive head trauma.

Joshua L Goldstein, Daniel Leonhardt, Natalie Kmytyuk, Francine Kim, Deli Wang, Mark S Wainwright

Abstract read
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Early diffusion restriction of white matter in infants with small subdural hematomas is associated with delayed atrophy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Article
  5. Article
  6. An ounce of prevention but less than a pound of cure: seizure prophylaxis after intracranial hemorrhage.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2014
    Article
  7. Review
  8. Article
  9. Nonconvulsive electrographic seizures are common in children with abusive head trauma*.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Joshua L GoldsteinDivision of Neurology no. 51, Department of Pediatrics, Children's Memorial Hospital, Northwestern University Feinberg School of Medicine, 2300 Children's Plaza, Chicago, IL 60614, USA. jgoldstein@childrensmemorial.org
Daniel Leonhardt
Natalie Kmytyuk
Francine Kim
Deli Wang
Mark S Wainwright
Northwestern University · USComer Children's Hospital · USLurie Children's Hospital · USRandall Children's Hospital at Legacy Emanuel · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbusive head trauma (AHT) is a common condition in children. Little is known in this condition regarding the frequency of seizures, the factors associated with increased risk of seizures, or the association of seizures with outcome. We sought to determine frequency and risks for in-hospital seizures after AHT.

methodsThis was a single-center, retrospective chart review study at a 270 bed tertiary care referral pediatric hospital.

resultsA total of 54 cases of AHT were identified during the study period. During the first week following hospital admission, 33% of patients were observed to have clinical seizures. The occurrence of clinical seizures after admission was associated with findings on initial CT including midline shift, cerebral edema, and loss of gray white differentiation. MRI findings associated with clinical seizures after admission included midline shift, cerebral edema, infarction, and restricted diffusion. The presenting complaint of seizures or acute mental status changes well as a variety of abnormal imaging findings including gray white blurring, infarction, and edema were associated with short-term outcomes.

conclusionsSpecific neuroradiologic findings identify children at greater risk for seizures, both clinical and subclinical, following AHT. Clinical and subclinical seizures are common in the initial hospitalization for AHT.

Indexed as

Child AbuseHospitalizationBrain InjuriesChildChild, PreschoolFemaleHospitals, PediatricHumansInfantMagnetic Resonance ImagingMaleRetrospective StudiesSeizuresTomography, X-Ray Computed

Identifiers

PMID21042880
OpenAlexW2098315448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.