Evidence map›Paper›PMID 21040835›Full record

ArticleNeuron2010

Vesicle priming in a SNAP.

Martin Müller, Graeme W Davis

Abstract readComment
In one paragraph

Article in Neuron, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Martin MüllerDepartment of Biochemistry and Biophysics, 1550 4th Street, Rock Hall 4th Floor North, University of California, San Francisco, CA 94158, USA.
Graeme W Davis

Funding

GENETIC ANALYSIS OF SYNAPTIC HOMEOSTASISR01NS039313 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAVIS, GRAEME W · 2000 to 2016
$5.3M
TRANS-SYNAPTIC SIGNALING DURING NEUROMUSCULAR DEVELOPMENTR01NS059867 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAVIS, GRAEME W · 2008 to 2015
$2.7M
NINDS NIH HHS R01 NS039313NINDS NIH HHS R01 NS059867
6 · The paper itself

Abstract

In this issue of Neuron, Burgalossi et al. investigate synaptic vesicle priming by using presynaptic Ca(2+) uncaging at a small, glutamatergic, central synapse. Combining this technique with mouse genetics, the authors demonstrate that vesicle priming during ongoing neural activity can be limited by the recycling of recently used SNARE complexes.

Identifiers

PMID21040835
PMCPMC4372602

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.