ReviewProgress in biophysics and molecular biology2011
Theoretical models for coronary vascular biomechanics: progress & challenges.
Review in Progress in biophysics and molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 72 citations in OpenAlex.
- Coronary wave intensity during the Valsalva manoeuvre in humans reflects altered intramural vessel compression responsible for extravascular resistance.The Journal of physiology · 2012Trial
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- GLP-1 Receptor Agonists and Myocardial Perfusion: Bridging Mechanisms to Clinical Outcomes.International journal of molecular sciences · 2025Review
- An agent-based model of cardiac allograft vasculopathy: toward a better understanding of chronic rejection dynamics.Frontiers in bioengineering and biotechnology · 2023Article
- Network-driven anomalous transport is a fundamental component of brain microvascular dysfunction.Nature communications · 2021Article
- Coronary remodeling and biomechanics: Are we going with the flow in 2020?American journal of physiology. Heart and circulatory physiology · 2021Review
- A Numerical Model for Simulating the Hemodynamic Effects of Enhanced External Counterpulsation on Coronary Arteries.Frontiers in physiology · 2021Article
- Vulnerable Plaque, Characteristics, Detection, and Potential Therapies.Journal of cardiovascular development and disease · 2019Review
- Dynamic Changes in Microvascular Flow Conductivity and Perfusion After Myocardial Infarction Shown by Image-Based Modeling.Journal of the American Heart Association · 2019Article
- Characterization of receptor binding kinetics for vascular endothelial growth factor-A using SPR.Analytical biochemistry · 2019Article
- Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis.Scientific reports · 2018Article
- Article
- BeatBox-HPC simulation environment for biophysically and anatomically realistic cardiac electrophysiology.PloS one · 2017Article
- Heterogeneous mechanics of the mouse pulmonary arterial network.Biomechanics and modeling in mechanobiology · 2016Article
- A mathematical model of coronary blood flow control: simulation of patient-specific three-dimensional hemodynamics during exercise.American journal of physiology. Heart and circulatory physiology · 2016Article
- Peptide-modified zwitterionic porous hydrogels for endothelial cell and vascular engineering.BioResearch open access · 2014Article
- Structure and response to flow of the glycocalyx layer.Biophysical journal · 2014Article
- A new flow-regulating cell type in the Demosponge Tethya wilhelma - functional cellular anatomy of a leuconoid canal system.PloS one · 2014Article
- Myocardial perfusion distribution and coronary arterial pressure and flow signals: clinical relevance in relation to multiscale modeling, a review.Medical & biological engineering & computing · 2013Review
- Myocardial-vessel interaction: role of LV pressure and myocardial contractility.Medical & biological engineering & computing · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 4 countries.
Funding
Abstract
A key aim of the cardiac Physiome Project is to develop theoretical models to simulate the functional behaviour of the heart under physiological and pathophysiological conditions. Heart function is critically dependent on the delivery of an adequate blood supply to the myocardium via the coronary vasculature. Key to this critical function of the coronary vasculature is system dynamics that emerge via the interactions of the numerous constituent components at a range of spatial and temporal scales. Here, we focus on several components for which theoretical approaches can be applied, including vascular structure and mechanics, blood flow and mass transport, flow regulation, angiogenesis and vascular remodelling, and vascular cellular mechanics. For each component, we summarise the current state of the art in model development, and discuss areas requiring further research. We highlight the major challenges associated with integrating the component models to develop a computational tool that can ultimately be used to simulate the responses of the coronary vascular system to changing demands and to diseases and therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.