ArticleNeuropsychology2010
Latent structure and factorial invariance of a neuropsychological test battery for the study of preclinical Alzheimer's disease.
Article in Neuropsychology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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Who cites it
75 citing papers in PubMed, 99 citations in OpenAlex.
- Obtaining comparable measurement of midlife cognitive functioning from disparate cognitive tasks.Neuropsychology · 2026Article
- Validation of longitudinal change in proper name recall with pTau217 as a marker of early cognitive decline in cognitively unimpaired adults at risk for Alzheimer's disease dementia.Journal of Alzheimer's disease : JAD · 2026Article
- Redefining cognitive testing: the impact of cognitive reserve and sex from early to late adulthood.Frontiers in psychology · 2026Article
- Sex modifies the association between cardiorespiratory fitness and insulin resistance in adults at risk for Alzheimer's disease.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2025Observational
- Observational
- Unveiling the sound of the cognitive status: Machine Learning-based speech analysis in the Alzheimer's disease spectrum.Alzheimer's research & therapy · 2024Article
- TWINGEN - protocol for an observational clinical biobank recall and biomarker study to identify individuals with high risk of Alzheimer's disease.medRxiv : the preprint server for health sciences · 2023Article
- Gray matter volume and within-task verbal fluency performance among older adults.Brain and cognition · 2023Article
- Why a clinical trial is as good as its outcome measure: A framework for the selection and use of cognitive outcome measures for clinical trials of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Neuropsychological networks in cognitively healthy older adults and dementia patients.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022Article
- Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women.Annals of neurology · 2022Article
- Cardiorespiratory fitness and cognition in persons at risk for Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Age-related differences in white matter microstructure measured by advanced diffusion MRI in healthy older adults at risk for Alzheimer's disease.Aging brain · 2022Article
- Latent Factor Structure and Measurement Invariance of the NIH Toolbox Cognition Battery in an Alzheimer's Disease Research Sample.Journal of the International Neuropsychological Society : JINS · 2021Article
- Temporal contiguity and ageing: The role of memory organization in cognitive decline.Journal of neuropsychology · 2021Article
- Association between composite scores of domain-specific cognitive functions and regional patterns of atrophy and functional connectivity in the Alzheimer's disease spectrum.NeuroImage. Clinical · 2021Article
- Subtle cognitive impairment as a marker of Alzheimer's pathologies and clinical progression in cognitively normal individuals.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021Article
- SNAFU: The Semantic Network and Fluency Utility.Behavior research methods · 2020Article
- Serum vitamin BThe British journal of nutrition · 2020Article
- The Uniform Dataset 3.0 Neuropsychological Battery: Factor Structure, Invariance Testing, and Demographically Adjusted Factor Score Calculation.Journal of the International Neuropsychological Society : JINS · 2020Article
15 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo examine the latent structure of a test battery currently being used in a longitudinal study of asymptomatic middle-aged adults with a parental history of Alzheimer's disease (AD) and test the invariance of the factor solution across subgroups defined by selected demographic variables and known genetic risk factors for AD.
methodAn exploratory factor analysis (EFA) and a sequence of confirmatory factor analyses (CFA) were conducted on 24 neuropsychological measures selected to provide a comprehensive estimate of cognitive abilities most likely to be affected in preclinical AD. Once the underlying latent model was defined and the structural validity established through model comparisons, a multigroup confirmatory factor analysis model was used to test for factorial invariance across groups.
resultsThe EFA solution revealed a factor structure consisting of five constructs: verbal ability, visuospatial ability, speed & executive function, working memory, and verbal learning & memory. The CFA models provided support for the hypothesized 5-factor structure. Results indicated factorial invariance of the model across all groups examined.
conclusionsCollectively, the results suggested a relatively strong psychometric basis for using the factor structure in clinical samples that match the characteristics of this cohort. This confirmed an invariant factor structure should prove useful in research aimed to detect the earliest cognitive signature of preclinical AD in similar middle aged cohorts.
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