ReviewPediatric endocrinology reviews : PER2010
Pediatric brain tumor treatment: growth consequences and their management.
Review in Pediatric endocrinology reviews : PER, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- The current status of FLASH particle therapy: a systematic review.Physical and engineering sciences in medicine · 2023Pooled it
- Growth Outcomes and Relapse Risk in Pediatric Medulloblastoma Survivors with and Without Growth Hormone Therapy: A 23-Year Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- Long-Term Outcomes of Radiation Therapy for Pediatric Brain Tumors: A Single-Center Study.Cureus · 2025Article
- Immune checkpoint inhibitors and endocrinopathies in pediatric brain tumor patients.Journal of pediatric endocrinology & metabolism : JPEM · 2025Article
- Gastrostomy tube feeding in children: a single-center experience.BMC gastroenterology · 2025Article
- Clinico-Demographic Profile of Paediatric Patients with Primary Intracranial Tumours in South India.Indian journal of surgical oncology · 2024Article
- Drivers Underlying Metastasis and Relapse in Medulloblastoma and Targeting Strategies.Cancers · 2024Review
- Zebrafish Models of Paediatric Brain Tumours.International journal of molecular sciences · 2022Review
- Article
- Neuropilin-1: A Key Protein to Consider in the Progression of Pediatric Brain Tumors.Frontiers in oncology · 2021Review
- Reliable change in pediatric brain tumor: A preliminary investigation.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2020Article
- Differential trajectories of neurocognitive functioning in females versus males following treatment for pediatric brain tumors.Neuro-oncology · 2019Article
- Normal tissue damage: its importance, history and challenges for the future.The British journal of radiology · 2019Review
- Article
- Manganese-containing Prussian blue nanoparticles for imaging of pediatric brain tumors.International journal of nanomedicine · 2014Article
- Gliomas in children.Current treatment options in neurology · 2013Article
- Radiosurgery with photons or protons for benign and malignant tumours of the skull base: a review.Radiation oncology (London, England) · 2012Review
- Prevalence of Endocrine Disorders in Childhood Brain Tumor Survivors in South Korea.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Tumors of the central nervous system, the most common solid tumors of childhood, are a major source of cancer-related morbidity and mortality in children. Survival rates have improved significantly following treatment for childhood brain tumors, with this growing cohort of survivors at high risk of adverse medical and late effects. Endocrine morbidities are the most prominent disorder among the spectrum of longterm conditions, with growth hormone deficiency the most common endocrinopathy noted, either from tumor location or after cranial irradiation and treatment effects on the hypothalamic/pituitary unit. Deficiency of other anterior pituitary hormones can contribute to negative effects on growth, body image and composition, sexual function, skeletal health, and quality of life. Pediatric and adult endocrinologists often provide medical care to this increasing population. Therefore, a thorough understanding of the epidemiology and pathophysiology of growth failure as a consequence of childhood brain tumor, both during and after treatment, is necessary and the main focus of this review.
Indexed as
Identifiers
21037539PMC4148717W65917634What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.