SynthesisThe British journal of psychiatry : the journal of mental science2010
Early intervention services, cognitive-behavioural therapy and family intervention in early psychosis: systematic review.
Synthesis in The British journal of psychiatry : the journal of mental science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 16 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
139 citing papers in PubMed, 16 syntheses or guidelines pooled it, 470 citations in OpenAlex.
- A systematic review of specialized psychosocial and complex psychosocial interventions for early psychosis, early depression, early bipolar disorder, and early borderline personality disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2026Pooled it
- Family-based interventions versus standard care for people with schizophrenia.The Cochrane database of systematic reviews · 2024Pooled it
- Cognitive behavioural therapy added to standard care for first-episode and recent-onset psychosis.The Cochrane database of systematic reviews · 2024Pooled it
- Cognitive-behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis.Health technology assessment (Winchester, England) · 2021Pooled it
- Establishing a clinical service to prevent psychosis: What, how and when? Systematic review.Translational psychiatry · 2021Pooled it
- Schizophrenia.Deutsches Arzteblatt international · 2020Pooled it
- Effectiveness of Family Intervention for Preventing Relapse in First-Episode Psychosis Until 24 Months of Follow-up: A Systematic Review With Meta-analysis of Randomized Controlled Trials.Schizophrenia bulletin · 2020Pooled it
- Psychological interventions in psychosis in children and adolescents: a systematic review.European child & adolescent psychiatry · 2019Pooled it
- Attenuated psychotic symptom interventions in youth at risk of psychosis: A systematic review and meta-analysis.Early intervention in psychiatry · 2019Pooled it
- Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression.JAMA psychiatry · 2018Pooled it
- Pooled it
- The role of untreated psychosis in neurodegeneration: a review of hypothesized mechanisms of neurotoxicity in first-episode psychosis.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2014Pooled it
- Parental communication and psychosis: a meta-analysis.Schizophrenia bulletin · 2014Pooled it
- A systematic review and meta-analysis of recovery in schizophrenia.Schizophrenia bulletin · 2013Pooled it
- Early interventions to prevent psychosis: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2013Pooled it
- Predicting the risk of psychosis onset: advances and prospects.Early intervention in psychiatry · 2012Pooled it
- Effectiveness of implementing family involvement on patient outcomes in individuals with psychotic disorders: a pragmatic cluster randomised controlled trial.BMC psychiatry · 2025Trial
- Efficacy of Individual Placement and Support (IPS) on Employment, Education, and Training in Young Adults With Early Psychosis-A Randomized Controlled Trial.Brain and behavior · 2025Trial
- Trial
- A Randomised Controlled Trial of a Caregiver-Facilitated Problem-Solving Based Self-Learning Program for Family Carers of People with Early Psychosis.International journal of environmental research and public health · 2020Trial
79 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundEarly intervention services for psychosis aim to detect emergent symptoms, reduce the duration of untreated psychosis, and improve access to effective treatments.
aimsTo evaluate the effectiveness of early intervention services, cognitive-behavioural therapy (CBT) and family intervention in early psychosis.
methodSystematic review and meta-analysis of randomised controlled trials of early intervention services, CBT and family intervention for people with early psychosis.
resultsEarly intervention services reduced hospital admission, relapse rates and symptom severity, and improved access to and engagement with treatment. Used alone, family intervention reduced relapse and hospital admission rates, whereas CBT reduced the severity of symptoms with little impact on relapse or hospital admission.
conclusionsFor people with early psychosis, early intervention services appear to have clinically important benefits over standard care. Including CBT and family intervention within the service may contribute to improved outcomes in this critical period. The longer-term benefits of this approach and its component treatments for people with early and established psychosis need further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.