Evidence map›Paper›PMID 21037211›Full record

SynthesisThe British journal of psychiatry : the journal of mental science2010

Early intervention services, cognitive-behavioural therapy and family intervention in early psychosis: systematic review.

Victoria Bird, Preethi Premkumar, Tim Kendall, Craig Whittington, Jonathan Mitchell, Elizabeth Kuipers

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The British journal of psychiatry : the journal of mental science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 16 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 16 syntheses or guidelines pooled it, 470 citations in OpenAlex.

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  6. Schizophrenia.Deutsches Arzteblatt international · 2020
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79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Victoria BirdNational Collaborating Centre for Mental Health, Royal College of Psychiatrists' Research and Training Unit, Standon House, 21 Mansell Street, London E1 8AA, UK. vbird@cru.rcpsych.ac.uk
Preethi Premkumar
Tim Kendall
Craig Whittington
Jonathan Mitchell
Elizabeth Kuipers
King's College London · GBCentre for Mental Health · GBRoyal College of Psychiatrists · GBSheffield Health and Social Care NHS Foundation Trust · GBUniversity College London · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundEarly intervention services for psychosis aim to detect emergent symptoms, reduce the duration of untreated psychosis, and improve access to effective treatments.

aimsTo evaluate the effectiveness of early intervention services, cognitive-behavioural therapy (CBT) and family intervention in early psychosis.

methodSystematic review and meta-analysis of randomised controlled trials of early intervention services, CBT and family intervention for people with early psychosis.

resultsEarly intervention services reduced hospital admission, relapse rates and symptom severity, and improved access to and engagement with treatment. Used alone, family intervention reduced relapse and hospital admission rates, whereas CBT reduced the severity of symptoms with little impact on relapse or hospital admission.

conclusionsFor people with early psychosis, early intervention services appear to have clinically important benefits over standard care. Including CBT and family intervention within the service may contribute to improved outcomes in this critical period. The longer-term benefits of this approach and its component treatments for people with early and established psychosis need further research.

Indexed as

Cognitive Behavioral TherapyFamily TherapyMental Health ServicesEarly DiagnosisHospitalizationHumansPatient Acceptance of Health CarePsychiatric Status Rating ScalesPsychotic DisordersRandomized Controlled Trials as TopicSecondary PreventionSeverity of Illness IndexTime FactorsTreatment Outcome

Identifiers

PMID21037211
PMCPMC2966501
OpenAlexW2135059788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.