ReviewMayo Clinic proceedings2010
Energy beverages: content and safety.
Review in Mayo Clinic proceedings, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed, 4 syntheses or guidelines pooled it, 393 citations in OpenAlex.
- Energy Drinks as the Legal Cocaine? A Comparative Review of Cardiac Physiopathological and Histopathological Patterns.Cardiovascular toxicology · 2025Pooled it
- Prevalence and characterisation of energy drink consumption in Europe: a systematic review.Public health nutrition · 2025Pooled it
- Healthy Behavior and Sports Drinks: A Systematic Review.Nutrients · 2023Pooled it
- Pooled it
- Impact of Acute Energy Drink Consumption on Heart Rate Variability in Children and Adolescents. A Randomized Trial.Pediatric cardiology · 2026Trial
- Effect of antenatal use of high energy nutritional supplements on cardio metabolic risk markers in underweight primi gravidas; a randomized controlled trial.BMC pregnancy and childbirth · 2024Trial
- Energy drinks: effects on pediatric 24-h ambulatory blood pressure monitoring. A randomized trial.Pediatric research · 2023Trial
- Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial.Sensors (Basel, Switzerland) · 2022Trial
- Caffeine-Containing Energy Shots Cause Acute Impaired Glucoregulation in Adolescents.Nutrients · 2020Trial
- A randomized, placebo-controlled crossover trial of a decaffeinated energy drink shows no significant acute effect on mental energy.The American journal of clinical nutrition · 2020Trial
- Impact of High Volume Energy Drink Consumption on Electrocardiographic and Blood Pressure Parameters: A Randomized Trial.Journal of the American Heart Association · 2019Trial
- Acute effects of energy drinks in medical students.European journal of nutrition · 2017Trial
- Short-Term Effects of a Ready-to-Drink Pre-Workout Beverage on Exercise Performance and Recovery.Nutrients · 2017Trial
- Effects of acute ingestion of a pre-workout dietary supplement with and withoutJournal of the International Society of Sports Nutrition · 2017Trial
- Cardio- and cerebrovascular responses to the energy drink Red Bull in young adults: a randomized cross-over study.European journal of nutrition · 2014Trial
- Phytotherapy in Sports Performance and Recovery: A Bibliometric Mapping of Research Themes and Trends.Sports (Basel, Switzerland) · 2026Article
- Concomitant intake of high levels of monosodium glutamate and taurine induces adverse effects in the rat brain.Toxicology reports · 2026Article
- Review
- Taurine Alleviates Sepsis-Induced Myocardial Injury by Inhibiting NF-κB Pathway-Mediated Inflammation, Mitochondrial Dysfunction, and Apoptosis.Cardiovascular toxicology · 2026Article
- Effects of energy drinks on fertility, blood parameters and perinatal physiology in female rats.Revista da Escola de Enfermagem da U S P · 2026Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise is making a resurgence in many countries, given its benefits for fitness as well as prevention of obesity. This trend has spawned many supplements that purport to aid performance, muscle growth, and recovery. Initially, sports drinks were developed to provide electrolyte and carbohydrate replacement. Subsequently, energy beverages (EBs) containing stimulants and additives have appeared in most gyms and grocery stores and are being used increasingly by "weekend warriors" and those seeking an edge in an endurance event. Long-term exposure to the various components of EBs may result in significant alterations in the cardiovascular system, and the safety of EBs has not been fully established. For this review, we searched the MEDLINE and EMBASE databases from 1976 through May 2010, using the following keywords: energy beverage, energy drink, power drink, exercise, caffeine, red bull, bitter orange, glucose, ginseng, guarana, and taurine. Evidence regarding the effects of EBs is summarized, and practical recommendations are made to help in answering the patient who asks, "Is it safe for me to drink an energy beverage when I exercise?"
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.