Evidence map›Paper›PMID 21036826›Full record

ArticleThe American journal of tropical medicine and hygiene2010

Longitudinal studies of Plasmodium falciparum malaria in pregnant women living in a rural Cameroonian village with high perennial transmission.

Rose F G Leke, Jude D Bioga, James Zhou, Genevieve G Fouda, Robert J I Leke, Viviane Tchinda, Rosette Megnekou, Josephine Fogako, Grace Sama, Philomina Gwanmesia and 5 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rose F G LekeFaculty of Medicine and Biomedical Research, The Biotechnology Center, University of Yaoundé 1, Yaoundé, Cameroon. roseleke@yahoo.com
Jude D Bioga
James Zhou
Genevieve G Fouda
Robert J I Leke
Viviane Tchinda
Rosette Megnekou
Josephine Fogako
Grace Sama
Philomina Gwanmesia
Germaine Bomback
Charles Nama
Ababacar Diouf
Naveen Bobbili
Diane Wallace Taylor

Funding

TH2 BIAS EFFECT ON MALARIAL IMMUNITY IN CAMEROONU01AI043888 · NIAID · GEORGETOWN UNIVERSITY · PI TAYLOR, DIANE WALLACE · 1998 to 2002
$2.7M
NIAID NIH HHS U01 AI043888NIAID NIH HHS UO1 AI43888
6 · The paper itself

Abstract

A prospective longitudinal study of Plasmodium falciparum in pregnant women was conducted in the rural village of Ngali II, where malaria is hyperendemic and individuals receive ~0.7 infectious mosquito bites/person/day throughout the year. Pregnant women (N = 60; 19 primigravidae, 41 multigravidae) were enrolled early in pregnancy (median 14 wk) and were followed monthly, with 38 women followed through term (5.7 ± 1.1 prenatal visits and delivery). The total number of times primigravidae were slide-positive during pregnancy was higher than multigravidae (3.3 ± 1.1 versus 1.3 ± 1.3 times; P < 0.001), but no difference in the number of polymerase chain reaction-positive cases (4.6 ± 1.7 and 3.4 ± 1.7 times, P = 0.106) or total genotypes they harbored (8.9 ± 3.2 and 7.0 ± 2.9) was found. Only 7.9% women developed symptomatic infections. All primigravidae and 38% multigravidae were placental malaria-positive at delivery (P = 0.009). Genotyping showed that 77% of placental parasites were acquired ≥ 30 wks in pregnancy. These results help identify the extent of malaria-associated changes women experience during pregnancy.

Indexed as

AdolescentAdultAgedAnimalsAnophelesCameroonChildChild, PreschoolFemaleHumansInfantInfant, NewbornLongitudinal StudiesMalaria, FalciparumMaleMiddle Aged

Identifiers

PMID21036826
PMCPMC2963958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.