Evidence map›Paper›PMID 21035841›Full record

ReviewLancet (London, England)2010

Operational strategies to achieve and maintain malaria elimination.

Bruno Moonen, Justin M Cohen, Robert W Snow, Laurence Slutsker, Chris Drakeley, David L Smith, Rabindra R Abeyasinghe, Mario Henry Rodriguez, Rajendra Maharaj, Marcel Tanner and 1 more

3 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lancet (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 265 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
265citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02610400 phase3completednot on this mapstarted 2016, after this paper: background citation

Targeted Parasite Elimination in the Human and Mosquito to Reduce Malaria Transmission: A Cluster Randomised Controlled Factorial Design Trial of Reactive Focal Drug Administration (rfMDA) Versus Reactive Case Detection (RACD), With and Without Reactive Vector Control (RAVC), From the Low Endemic Setting of Namibia

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2017Enrolled9,845ConditionsMalariaArmsRACD, RAVC, rfMDA
NCT04416945 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

Targeting High-risk Populations With Enhanced Reactive Case Detection: a Study to Assess the Effectiveness and Feasibility for Reducing Plasmodium Falciparum and P. Vivax Malaria in Southern Lao Peoples Democratic Republic

TypeinterventionalSponsorUniversity of California, San FranciscoRan2020 to 2021Enrolled0ConditionsPlasmodium Falciparum Malaria, Plasmodium Vivax MalariaArmsHousehold Reactive Case Detection, RACD of cases' co-workers/co-travelers, Case Management and Follow-up
NCT05052502 nacompletednot on this mapstarted 2020, after this paper: background citation

Targeting High-risk Populations With Enhanced Reactive Focal Mass Drug Administration: A Study to Assess the Effectiveness and Feasibility for Plasmodium Falciparum and Plasmodium Vivax Malaria in Thailand

TypeinterventionalSponsorUniversity of California, San FranciscoRan2020 to 2022Enrolled14,977ConditionsPlasmodium Falciparum Malaria, Plasmodium Vivax MalariaArmsCase Management and Follow-up, Reactive focal mass drug administration (rfMDA)
3 · Its place in the literature

Who cites it

265 citing papers in PubMed, 1 synthesis or guideline pooled it.

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205 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Bruno MoonenClinton Health Access Initiative, Nairobi, Kenya. bmoonen@clintonhealthaccess.org
Justin M Cohen
Robert W Snow
Laurence Slutsker
Chris Drakeley
David L Smith
Rabindra R Abeyasinghe
Mario Henry Rodriguez
Rajendra Maharaj
Marcel Tanner
Geoffrey Targett

Funding

Wellcome Trust 078925Wellcome Trust 079080
6 · The paper itself

Abstract

Present elimination strategies are based on recommendations derived during the Global Malaria Eradication Program of the 1960s. However, many countries considering elimination nowadays have high intrinsic transmission potential and, without the support of a regional campaign, have to deal with the constant threat of imported cases of the disease, emphasising the need to revisit the strategies on which contemporary elimination programmes are based. To eliminate malaria, programmes need to concentrate on identification and elimination of foci of infections through both passive and active methods of case detection. This approach needs appropriate treatment of both clinical cases and asymptomatic infections, combined with targeted vector control. Draining of infectious pools entirely will not be sufficient since they could be replenished by imported malaria. Elimination will thus additionally need identification and treatment of incoming infections before they lead to transmission, or, more realistically, embarking on regional initiatives to dry up importation at its source.

Indexed as

Asymptomatic DiseasesHumansMalariaMosquito Control

Identifiers

PMID21035841
PMCPMC3037542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.