Trial reportAppetite2011
Impact of exercise and dietary fatty acid composition from a high-fat diet on markers of hunger and satiety.
Trial report in Appetite, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 51 citations in OpenAlex.
- Fat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial.The Journal of nutrition · 2026Trial
- Palmitic acid in the sn-2 position decreases glucose-dependent insulinotropic polypeptide secretion in healthy adults.European journal of clinical nutrition · 2014Trial
- Satiety, but not total PYY, Is increased with continuous and intermittent exercise.Obesity (Silver Spring, Md.) · 2013Trial
- Interactions between exercise, environmental factors, and diet in modulating appetite-regulating hormones: implications for athletes and physically active individuals.Korean journal of family medicine · 2025Article
- Dietary Lipids, Gut Microbiota, and Their Metabolites: Insights from Recent Studies.Nutrients · 2025Review
- Endurance training promotes the browning of WAT by enhancing the NPFF pathway in the hypothalamus in rats with type 2 diabetes.Iranian journal of basic medical sciences · 2025Article
- Impact of Resistance and Endurance Training on Ghrelin and Plasma Leptin Levels in Overweight and Obese Subjects.International journal of molecular sciences · 2024Review
- Exercise and Weight Management: The Role of Leptin-A Systematic Review and Update of Clinical Data from 2000-2022.Journal of clinical medicine · 2023Review
- Differential Effects of Monounsaturated and Polyunsaturated Fats on Satiety and Gut Hormone Responses in Healthy Subjects.Foods (Basel, Switzerland) · 2019Article
- Appetite responses to high-fat meals or diets of varying fatty acid composition: a comprehensive review.European journal of clinical nutrition · 2017Review
- The Effect of Exercise Intensity on Total PYY and GLP-1 in Healthy Females: A Pilot Study.Journal of nutrition and metabolism · 2017Article
- The effect of eight weeks endurance training and high-fat diet on appetite-regulating hormones in rat plasma.Iranian journal of basic medical sciences · 2014Article
- Influence of running and walking on hormonal regulators of appetite in women.Journal of obesity · 2012Article
- Determinants of appetite ratings: the role of age, gender, BMI, physical activity, smoking habits, and diet/weight concern.Food & nutrition research · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
To compare the effects of both dietary fatty acid composition and exercise vs. sedentary conditions on circulating levels of hunger and satiety hormones. Eight healthy males were randomized in a 2 × 2 crossover design. The four treatments were 3 days of HF diets (50% of energy) containing high saturated fat (22% of energy) with exercise (SE) or sedentary (SS) conditions, and high monounsaturated fat (30% of energy) with exercise (UE) or sedentary (US) conditions. Cycling exercise was completed at 45% of VO(2)max for 2h daily. On the third HF day, 20 blood samples were drawn over a 24h period for each hormone (leptin, insulin, ghrelin, and peptide YY (PYY)). A visual analog scale (VAS) was completed hourly between 0800 and 2200. Average 24h leptin and insulin levels were lower while 24h PYY was higher during exercise vs. sedentary conditions. FA composition did not differentially affect 24h hormone values. VAS scores for hunger and fullness did not differ between any treatment but did correlate with ghrelin, leptin, and insulin. High saturated or unsaturated fat diets did not differ with respect to markers of hunger or satiety. Exercise decreased 24h leptin and insulin while increasing PYY regardless of FA composition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.