Evidence map›Paper›PMID 21034975›Full record

ReviewAdvances in immunology2010

Bronchus-associated lymphoid tissue (BALT) structure and function.

Troy D Randall

Open access · greenAbstract readReview
In one paragraph

Review in Advances in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 1 pooled it
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 1 synthesis or guideline pooled it, 250 citations in OpenAlex.

  1. Mucosal immune response in biology, disease prevention and treatment.Signal transduction and targeted therapy · 2025
    Pooled it
  2. Review
  3. B cell-intrinsic CXCR3 drives efficient generation of ectopic pulmonary germinal center responses to influenza A virus infection.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Frontiers in immunology · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. CD4Immunology and cell biology · 2025
    Review
  11. Towards early detection and disease interception of COPD across the lifespan.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Troy D RandallDepartment of Medicine, Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA.
University of Rochester Medical Center · US

Funding

Generation of effective memory CD8 T cells to influenzaR01AI061511 · NIAID · UNIVERSITY OF ROCHESTER · PI RANDALL, TROY D · 2005 to 2009
$1.8M
Function of NALT in nasal immunization to heterotypic strains of influenzaR01AI072689 · NIAID · UNIVERSITY OF ROCHESTER · PI RANDALL, TROY D · 2007 to 2010
$1.5M
NHLBI NIH HHS HL69489NIAID NIH HHS AI61511NIAID NIH HHS AI72689NIAID NIH HHS R01 AI061511NIAID NIH HHS R01 AI072689
6 · The paper itself

Abstract

Bronchus-associated lymphoid tissue (BALT) is a constitutive mucosal lymphoid tissue adjacent to major airways in some mammalian species, including rats and rabbits, but not humans or mice. A related tissue, inducible BALT (iBALT), is an ectopic lymphoid tissue that is formed upon inflammation or infection in both mice and humans and can be found throughout the lung. Both BALT and iBALT acquire antigens from the airways and initiate local immune responses and maintain memory cells in the lungs. Here, we discuss the development and function of BALT and iBALT in the context of pulmonary immunity to infectious agents, tumors, and allergens as well as autoimmunity and inflammatory diseases of the lung.

Indexed as

AnimalsBronchiHumansImmunity, MucosalLymphocyte ActivationLymphocytesLymphoid TissueRespiratory Mucosa

Identifiers

PMID21034975
PMCPMC7150010
OpenAlexW186823463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.