Evidence map›Paper›PMID 21030245›Full record

ReviewCurrent opinion in biotechnology2010

Biologically active secondary metabolites from marine cyanobacteria.

Joshawna K Nunnery, Emily Mevers, William H Gerwick

Abstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Deciphering guanidine assimilation and riboswitch-based gene regulation in cyanobacteria for synthetic biology applications.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Environmental risk factors for liver cancer.Hepatology (Baltimore, Md.) · 2025
    Article
  7. Review
  8. Fatuamide A, a Hybrid PKS/NRPS Metallophore from aJournal of natural products · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. More than just an eagle killer: The freshwater cyanobacteriumProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  18. Article
  19. Article
  20. Laser Treatment Increases the Antimicrobial Efficacy of Cyanobacterial Extracts againstInternational journal of environmental research and public health · 2022
    Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joshawna K NunneryScripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Emily Mevers
William H Gerwick

Funding

Targeted Discovery of Marine-derived Anticancer LeadsU19CA052955 · NCI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI GERWICK, WILLIAM HENRY · 1995 to 2009
$9.7M
Neurotoxins from Marine Algae and CyanobacteriaR01NS053398 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GERWICK, WILLIAM HENRY, MURRAY, THOMAS F · 2005 to 2015
$4.3M
Discovery of Anticancer Drugs from CyanophytesR01CA100851 · NCI · HENRY FORD HEALTH SYSTEM · PI VALERIOTE, FREDERICK AUGUSTUS · 2004 to 2013
$3.8M
NCI NIH HHS CA100851NCI NIH HHS R01 CA100851NCI NIH HHS U19 CA052955NCI NIH HHS U19CA52955NINDS NIH HHS NS053398NINDS NIH HHS R01 NS053398
6 · The paper itself

Abstract

Marine cyanobacteria are a rich source of complex bioactive secondary metabolites which derive from mixed biosynthetic pathways. Recently, several marine cyanobacterial natural products have garnered much attention due to their intriguing structures and exciting anti-proliferative or cancer cell toxic activities. Several other recently discovered secondary metabolites exhibit insightful neurotoxic activities whereas others are showing pronounced anti-inflammatory activity. A number of anti-infective compounds displaying activity against neglected diseases have also been identified, which include viridamides A and B, gallinamide A, dragonamide E, and the almiramides.

Indexed as

Anti-Infective AgentsAnti-Inflammatory AgentsBiological ProductsCyanobacteriaMarine BiologyAnti-Infective AgentsAnti-Inflammatory AgentsBiological Products

Identifiers

PMID21030245
PMCPMC3034308

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.