Evidence map›Paper›PMID 21030233›Full record

ReviewCurrent opinion in cell biology2010

Germ cell sex determination: a collaboration between soma and germline.

Sheryl M Murray, Shu Yuan Yang, Mark Van Doren

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Cells · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Trajectory mapping of the earlyGenome research · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Genetics · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sheryl M MurrayDepartment of Biology, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
Shu Yuan Yang
Mark Van Doren

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Sexual development of the Drosophila gonadR01GM084356 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 2009 to 2016
$2.9M
NIGMS NIH HHS R01 GM084356NIGMS NIH HHS T32 GM007231
6 · The paper itself

Abstract

Sex determination is regulated very differently in the soma vs. the germline, yet both processes are critical for the creation of the male and female gametes. In general, the soma plays an essential role in regulating sexual identity of the germline. However, in some species, such as Drosophila and mouse, the sex chromosome constitution of the germ cells makes an autonomous contribution to germline sexual development. Here we review how the soma and germline cooperate to determine germline sexual identity for some important model systems, the fly, the worm and the mouse, and discuss some of the implications of 'dual control' (soma plus germline) as compared to species where germline sex is dictated only by the surrounding soma.

Indexed as

AnimalsFemaleGene Expression Regulation, DevelopmentalGerm CellsMaleOocytesSex Determination ProcessesSpermatozoa

Identifiers

PMID21030233
PMCPMC2996260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.