ArticleEuropean journal of radiology2012
High-resolution CT for identify patients with smear-positive, active pulmonary tuberculosis.
Article in European journal of radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis.Science translational medicine · 2014Trial
- Impact of vitamin C deficiency on imaging patterns and ventilatory function in pulmonary tuberculosis.Frontiers in medicine · 2025Article
- Unlocking the potential of miRNAs in detecting pulmonary tuberculosis: prospects and pitfalls.Expert reviews in molecular medicine · 2024Review
- Exploring the Potential of Exosomes as Biomarkers in Tuberculosis and Other Diseases.International journal of molecular sciences · 2024Review
- Computed tomography findings in patients with pulmonary tuberculosis and diabetes at an infectious disease hospital in China: a retrospective cross-sectional study.BMC infectious diseases · 2023Article
- A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions.EMBO molecular medicine · 2022Article
- Micro-Computed Tomography Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in Three-dimensional Granuloma Morphology.American journal of respiratory and critical care medicine · 2021Article
- Article
- Ultralow-dose CT with knowledge-based iterative model reconstruction (IMR) in evaluation of pulmonary tuberculosis: comparison of radiation dose and image quality.European radiology · 2019Observational
- How radiology can help pulmonary tuberculosis diagnosis: analysis of 49 patients.La Radiologia medica · 2019Article
- The Predictive Value of Multidetector High Resolution Computed Tomography in Evaluation of Suspected Sputum Smear Negative Active Pulmonary Tuberculosis in Egyptian Zagazig University Hospital Patients.Polish journal of radiology · 2017Review
- A high-resolution computed tomography-based scoring system to differentiate the most infectious active pulmonary tuberculosis from community-acquired pneumonia in elderly and non-elderly patients.European radiology · 2014Article
- High resolution computed tomography findings in smear-negative pulmonary tuberculosis patients according to their culture status.Journal of thoracic disease · 2014Article
- Evaluation of the relationship between smear positivity and high-resolution CT findings in children with pulmonary tuberculosis.Polish journal of radiology · 2014Article
- A high resolution computer tomography scoring system to predict culture-positive pulmonary tuberculosis in the emergency department.PloS one · 2014Article
- Chest tuberculosis: Radiological review and imaging recommendations.The Indian journal of radiology & imagingArticle
- Diagnostic value of bronchoscopy in sputum-negative pulmonary tuberculosis patients and its correlation with clinicoradiological features.Annals of thoracic medicineArticle
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7 authors.
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Abstract
purposeThis study evaluates the use of high-resolution computed tomography (HRCT) to differentiate smear-positive, active pulmonary tuberculosis (PTB) from other pulmonary infections in the emergency room (ER) setting.
methodsOne hundred and eighty-three patients diagnosed with pulmonary infections in an ER were divided into an acid fast bacillus (AFB) smear-positive, active PTB group (G1=84) and a non-AFB smear-positive, pulmonary infection group (G2=99). HRCT images from a 64-Multidetector CT were analyzed, retrospectively, for the morphology, number, and segmental distribution of pulmonary lesions.
resultsUtilizing multivariate analysis, five variables were found to be independent risk factors predictive of G1: (1) consolidation involving the apex segment of right upper lobe, posterior segment of the right upper lobe, or apico-posterior segment of the left upper lobe; (2) consolidation involving the superior segment of the right or left lower lobe; (3) presence of a cavitary lesion; (4) presence of clusters of nodules; (5) absence of centrilobular nodules. A G1 prediction score was generated based on these 5 criteria to help differentiate G1 from G2. The area under the receiver operating characteristic (ROC) curve was 0.96 ± 0.012 in our prediction model. With an ideal cut-off point score of 3, the specificity, sensitivity, positive predictive value (PPV), and negative predictive value (NPV) are 90.9%, 96.4%, 90.0% and 96.8%, respectively.
conclusionThe use of this AFB smear-positive, active PTB prediction model based on 5 key HRCT findings may help ER physicians determine whether or not isolation is required while awaiting serial sputum smear results in high risk patients.
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