ReviewImmunology and allergy clinics of North America2010
The role of respiratory virus infections in childhood asthma inception.
Review in Immunology and allergy clinics of North America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 4 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- Association between childhood asthma and history of assisted reproduction techniques: a systematic review and meta-analysis.European journal of pediatrics · 2021Pooled it
- Pooled it
- Maternal and cord blood vitamin D status and childhood infection and allergic disease: a systematic review.Nutrition reviews · 2016Pooled it
- A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years.BMJ open · 2014Pooled it
- Antiviral Efficacy of a Respiratory Syncytial Virus (RSV) Fusion Inhibitor in a Bovine Model of RSV Infection.Antimicrobial agents and chemotherapy · 2015Trial
- Incidence, viral etiology, and risk factors of wheezing in children under two years of age: findings from a low-income urban community in Dhaka, Bangladesh.BMC pulmonary medicine · 2026Article
- Clinical Profile and Hematologic Parameters of Children Under Five Years Presenting With Wheeze.Cureus · 2026Article
- Associations between dietary intake and asthma outcomes: Evidence from pooled analysis in two independent multiethnic Asian cohorts.The journal of allergy and clinical immunology. Global · 2026Article
- Clinical correlations with unmet social needs in critically ill children with asthma.The journal of allergy and clinical immunology. Global · 2025Article
- Lung functions and IgE component sensitizations: Five wheezing phenotypes in adolescents from the T-Child study in Tokyo.The journal of allergy and clinical immunology. Global · 2025Article
- Emergency management and asthma risk in young Medicaid-enrolled children with recurrent wheeze.The Journal of asthma : official journal of the Association for the Care of Asthma · 2024Article
- Article
- Early-life pulmonary viral infection leads to long-term functional and lower airway structural changes in the lungs.American journal of physiology. Lung cellular and molecular physiology · 2024Article
- Incidence and causative agent distribution of viral-induced paediatric asthma exacerbations under strict infection control measures: a single-centre retrospective study in Japan.BMC pulmonary medicine · 2023Article
- Burden and unmet need for specialist care in poorly controlled and severe childhood asthma in a Danish nationwide cohort.Respiratory research · 2023Article
- Persistent Airway Hyperresponsiveness Following Recovery from Infection with Pneumonia Virus of Mice.Viruses · 2021Article
- Wheezing-Related Relevant Factors and the Role of Viral Bronchiolitis.Frontiers in allergy · 2021Review
- Viral burden and diversity in acute respiratory tract infections in hospitalized children in wet and dry zones of Sri Lanka.PloS one · 2021Article
- Early-life respiratory syncytial virus lower respiratory tract infection in a South African birth cohort: epidemiology and effect on lung health.The Lancet. Global health · 2020Article
- Association of specific viral infections with childhood asthma exacerbations.Interventional medicine & applied science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Viral respiratory illnesses associated with wheezing are extremely common during early life and remain a frequent cause of morbidity and hospitalization in young children. Although many children who wheeze with respiratory viruses during infancy outgrow the problem, most children with asthma and reductions in lung function at school age begin wheezing during the first several years of life. Whether symptomatic viral infections of the lower respiratory tract are causal in asthma development or simply identify predisposed children remains a controversial issue. Wheezing illnesses caused by respiratory syncytial virus (RSV), particularly those severe enough to lead to hospitalization, have historically been associated with an increased risk of asthma at school age. However, with the development of molecular diagnostics, human rhinovirus (HRV) wheezing illnesses have been recognized more recently as a stronger predictor of school-age asthma than RSV. In this article, the authors review the impact of virus infections during early life, focusing primarily on RSV and HRV, and their potential roles in asthma inception.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.