ArticleCell2010
Monocytes join the dendritic cell family.
Article in Cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Characterization of circulating immune cells in acute Kawasaki disease suggests exposure to different antigens.Clinical and experimental immunology · 2020Trial
- Overlapping MHC class I/II Epitopes Program cDC1-like Differentiation of Monocyte-Derived Dendritic Cells via mTORC1 Signaling Inhibition.bioRxiv : the preprint server for biology · 2026Article
- Dysregulated immune cell responses in severe dengue pathogenesis.Frontiers in immunology · 2025Review
- CD16Blood advances · 2018Article
- Immunoproteomic identification and characterization of NiCell death & disease · 2017Article
- THP-1 cells as a model for human monocytes.Annals of translational medicine · 2016Article
- Phenotype and Function of CD209+ Bovine Blood Dendritic Cells, Monocyte-Derived-Dendritic Cells and Monocyte-Derived Macrophages.PloS one · 2016Article
- Dendritic cells in dengue virus infection: targets of virus replication and mediators of immunity.Frontiers in immunology · 2014Review
- Inflammatory spleen monocytes can upregulate CD11c expression without converting into dendritic cells.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections.PLoS pathogens · 2012Article
- Transcriptional regulation of macrophage polarization: enabling diversity with identity.Nature reviews. Immunology · 2011Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dendritic cells are professional antigen-presenting cells that mediate immunity and tolerance. Cheong et al. (2010) uncover a new route for dendritic cell production in vivo. They show that in response to infection by gram-negative bacteria, monocytes are recruited to the lymph node where they rapidly differentiate into dendritic cells that present antigens to T cells.
Identifiers
21029856What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.