ArticleEvidence-based complementary and alternative medicine : eCAM2011
Acupuncture on the Endometrial Morphology, the Serum Estradiol and Progesterone Levels, and the Expression of Endometrial Leukaemia-inhibitor Factor and Osteopontin in Rats.
Article in Evidence-based complementary and alternative medicine : eCAM, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Acupuncture in Uterine Fibroids Management: Literature Update on Frequently Used Acupoints and the Underlying Mechanism-A Narrative Review.Health science reports · 2025Review
- Acupuncture as an adjunct therapy for enhancing endometrial receptivity in female infertility: a literature review.Frontiers in physiology · 2025Review
- Acupuncture benefits to women with recurrent implantation failure: A propensity score-matched cohort study.Heliyon · 2023Article
- The Treatment of Complementary and Alternative Medicine on Female Infertility Caused by Endometrial Factors.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Multimodal Care for Headaches, Lumbopelvic Pain, and Dysmenorrhea in a Woman With Endometriosis: A Case Report.Journal of chiropractic medicine · 2021Article
- Article
- The Effects of Acupuncture on Pregnancy Outcomes of Recurrent Implantation Failure: A Systematic Review and Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Effects ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- Complementary Medicine Therapies That May Assist With Weight Loss: A Narrative Review.Journal of chiropractic medicine · 2019Review
- Acupuncture and women's health: an overview of the role of acupuncture and its clinical management in women's reproductive health.International journal of women's health · 2014Review
- Integrating acupuncture: are there positive health outcomes for women?Journal of Zhejiang University. Science. BReview
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although it is well known that acupuncture has beneficial effects on a variety of medical conditions especially in pain relief, nausea, and vomiting, it remains controversial whether it has positive impact on the female reproduction. The present study aimed to evaluate whether the following endometrial receptivity factors: the endometrial morphology, the hormone concentrations, and the protein expression of endometrial leukaemia-inhibitory factor (LIF) and osteopontin (OPN) could be improved by the acupuncture in clomiphene citrate(CC)-induced rat model during implantation period. Results showed that, compared with the CC group, glandular development advanced, the serum estradiol levels decreased significantly, and the glandular area and endometrial LIF and OPN expression were significantly higher in acupuncture group. There were no significant differences in serum progesterone levels, endometrial thickness, and stromal area between groups. These results suggest that acupuncture can improve certain aspects of endometrial receptivity in CC-induced rat model during implantation period, which might result in endometrial state better to female reproduction.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.