ArticleEvidence-based complementary and alternative medicine : eCAM2011
Antidiabetic Potentiality of the Aqueous-Methanolic Extract of Seed of Swietenia mahagoni (L.) Jacq. in Streptozotocin-Induced Diabetic Male Albino Rat: A Correlative and Evidence-Based Approach with Antioxidative and Antihyperlipidemic Activities.
Article in Evidence-based complementary and alternative medicine : eCAM, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 39 citations in OpenAlex.
- Ethnomedicinal Value of Antidiabetic Plants in Bangladesh: A Comprehensive Review.Plants (Basel, Switzerland) · 2021Review
- The recent use ofHeliyon · 2020Review
- Article
- Antidiabetic and Antidyslipidemic Activities of the Aqueous Extract ofIranian journal of medical sciences · 2017Article
- Protective Action of Carica papaya on β-Cells in Streptozotocin-Induced Diabetic Rats.International journal of environmental research and public health · 2016Article
- Traditional medicinal plants used for the treatment of diabetes in rural and urban areas of Dhaka, Bangladesh--an ethnobotanical survey.Journal of ethnobiology and ethnomedicine · 2013Article
- Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats.BMC complementary and alternative medicine · 2012Article
- Comprehensive Evaluation of Anti-hyperglycemic Activity of Fractionated Momordica charantia Seed Extract in Alloxan-Induced Diabetic Rats.Evidence-based complementary and alternative medicine : eCAM · 2012Article
- Antiatherosclerotic Potential of Active Principle Isolated from Eugenia jambolana in Streptozotocin-Induced Diabetic Rats.Evidence-based complementary and alternative medicine : eCAM · 2011Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antidiabetic, antioxidative, and antihyperlipidemic activities of aqueous-methanolic (2 : 3) extract of Swietenia mahagoni (L.) Jacq. (family Meliaceae) seed studied in streptozotocin-induced diabetic rats. Feeding with seed extract (25 mg 0.25 mL distilled water(-1)100 gm b.w.(-1)rat(-1) day(-1)) for 21 days to diabetic rat lowered the blood glucose level as well as the glycogen level in liver. Moreover, activities of antioxidant enzymes like catalase, peroxidase, and levels of the products of free radicals like conjugated diene and thiobarbituric acid reactive substances in liver, kidney, and skeletal muscles were corrected towards the control after this extract treatment in this model. Furthermore, the seed extract corrected the levels of serum urea, uric acid, creatinine, cholesterol, triglyceride, and lipoproteins towards the control level in this experimental diabetic model. The results indicated the potentiality of the extract of S. mahagoni seed for the correction of diabetes and its related complications like oxidative stress and hyperlipidemia. The extract may be a good candidate for developing a safety, tolerable, and promising neutraceutical treatment for the management of diabetes.
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