Evidence map›Paper›PMID 20981308›Full record

ArticleDermatology research and practice2010

Acne scars: pathogenesis, classification and treatment.

Gabriella Fabbrocini, M C Annunziata, V D'Arco, V De Vita, G Lodi, M C Mauriello, F Pastore, G Monfrecola

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Dermatology research and practice, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 120 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 12 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02025088 naunknown statusnot on this mapstarted 2013, after this paper: background citation

Comparison of Non-ablative Fractional Erbium Laser 1340nm and Microneedling for the Treatment of Atrophic Acne Scars: a Randomized Clinical Trial.

TypeinterventionalSponsorThaís Hofmann CachafeiroRan2013 to 2014Enrolled23ConditionsAcne, ScarArmsLaser, Microneedling
NCT04829370 nacompletednot on this mapstarted 2020, after this paper: background citation

Clinical Application of Patented Lyophilized PLT in Acne Scar Repairment.

TypeinterventionalSponsorShin Kong Wu Ho-Su Memorial HospitalRan2020 to 2020Enrolled15ConditionsAtrophic Acne ScarArmsPLT, Saline
NCT05704114 phase4completednot on this mapstarted 2021, after this paper: background citation

A Prospective, Single-center, Pilot Study to Evaluate the Efficacy, Safety, and Tolerability of Tazarotene 0.045% Lotion (Arazlo) for Treating Postinflammatory Erythema and Postinflammatory Hyperpigmentation in Subjects With Acne

TypeinterventionalSponsorDr. Emmy GraberRan2021 to 2022Enrolled20ConditionsAcne Vulgaris, Post Inflammatory Hyperpigmentation, Post Inflammatory Pigmentation Change, ErythemaArmsTazarotene 0.045% Lotion
3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 12 syntheses or guidelines pooled it, 419 citations in OpenAlex.

  1. Comparative Efficacy and Safety of Fractional COSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Pooled it
  2. Efficacy and Safety of Er:Glass versus COAesthetic plastic surgery · 2026
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. A meta-analysis of fractional COLasers in medical science · 2021
    Pooled it
  12. Interventions for acne scars.The Cochrane database of systematic reviews · 2016
    Pooled it
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Evaluation and comparison of the efficacy and safety of cross-linked and non-cross-linked hyaluronic acid in combination with botulinum toxin type A in the treatment of atrophic acne scars: A double-blind randomized clinical trial.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Trial

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gabriella FabbrociniDivision of Clinical Dermatology, Department of Systematic Pathology, University of Naples Federico II, Via Sergio Pansini 5, 80133 Napoli, Italy.
M C Annunziata
V D'Arco
V De Vita
G Lodi
M C Mauriello
F Pastore
G Monfrecola
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne has a prevalence of over 90% among adolescents and persists into adulthood in approximately 12%-14% of cases with psychological and social implications. Possible outcomes of the inflammatory acne lesions are acne scars which, although they can be treated in a number of ways, may have a negative psychological impact on social life and relationships. The main types of acne scars are atrophic and hypertrophic scars. The pathogenesis of acne scarring is still not fully understood, but several hypotheses have been proposed. There are numerous treatments: chemical peels, dermabrasion/microdermabrasion, laser treatment, punch techniques, dermal grafting, needling and combined therapies for atrophic scars: silicone gels, intralesional steroid therapy, cryotherapy, and surgery for hypertrophic and keloidal lesions. This paper summarizes acne scar pathogenesis, classification and treatment options.

Identifiers

PMID20981308
PMCPMC2958495
OpenAlexW2142384367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.