ArticleInternational journal of rheumatology2010
Vascular alterations and sexual function in systemic sclerosis.
Article in International journal of rheumatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Pregnancy outcomes in systemic sclerosis before and after diagnosis: a retrospective nationwide cohort study.Turkish journal of medical sciences · 2026Observational
- Sexual dysfunction among female patients with rheumatic diseases.Rheumatology international · 2024Article
- Uncovering the link between inflammatory rheumatic diseases and male reproductive health: a perspective on male infertility and sexual dysfunction.Rheumatology international · 2024Review
- The Impact of Systemic Sclerosis on Sexual Health: An Italian Survey.Healthcare (Basel, Switzerland) · 2023Article
- Poor maternal and foetal outcomes in women with systemic sclerosis: an interview-based study at a tertiary centre.Rheumatology international · 2021Observational
- Erectile Dysfunction in Systemic Sclerosis.Current rheumatology reports · 2016Review
- Sexual dysfunction in married women with Systemic Sclerosis.The Pan African medical journal · 2014Article
- Systemic sclerosis: current concepts in pathogenesis and therapeutic aspects of dermatological manifestations.Indian journal of dermatology · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sexual dysfunction is common in systemic sclerosis (SSc). Male erectile dysfunction (MED) has been reported in around 80% of subjects and more than half of female patients fulfill criteria for diagnosis as female sexual arousal Disorder (FSAD). While some evidence supports a role for cavernosal fibrosis, abundant data suggest that MED is yet another clinical feature of SSc related to vasculopathy. The contribution of vasculopathy to the more complex issues of female sexual dysfunction is less clear. Inhibitors of Type V phosphodiesterase are effective in men with MED secondary to SSc. Limited study in women suggests inconsistent effects on behavior (frequency) but not on measures related to perfusion. Sexual activity is an important component of quality of life and an important domain for the caregiver to address; it is not clear that it warrants primary consideration as a consistent measure of scleroderma-related vasculopathy.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.