ArticleInternational journal of pediatrics2010
Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review.
Article in International journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
149 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of maternal anemia on low-birth-weight in Sub-Sahara African countries: Systematic review and meta-analysis.PloS one · 2025Pooled it
- Maternal and Neonatal Characteristics and Outcomes of COVID-19 in Pregnancy: An Overview of Systematic Reviews.International journal of environmental research and public health · 2021Pooled it
- Maternal and neonatal outcomes associated with COVID-19 infection: A systematic review.PloS one · 2020Pooled it
- Clinical Characteristics and Neonatal Outcomes of Pregnant Patients With COVID-19: A Systematic Review.Frontiers in medicine · 2020Pooled it
- DAAM2 is elevated in the circulation and placenta in pregnancies complicated by fetal growth restriction and is regulated by hypoxia.Scientific reports · 2021Trial
- Understanding physiological adaptations of pregnancy to the chronic hypoxia of high altitude to inform obstetrical and neonatal care.Physiological reviews · 2026Review
- Correlation between Prenatal Fetal Hemodynamic Parameters and Growth Indices in Pregnant Women with Preeclampsia and Neonatal Ultrasound Indicators of Organ Development.Pakistan journal of medical sciences · 2026Article
- Decoding neurodevelopment risks of exposures to intoxication, infection, and trauma during pregnancy.Pregnancy (Hoboken, N.J.) · 2026Review
- Adaptation of the Transcriptome and miRNAome in Response to Hepatocellular Hypoxia.International journal of molecular sciences · 2026Article
- Optimized Open-Source Setting for Subjecting Rodents to Chronic Normobaric Hypoxia in Facilities with Minimal Nitrogen Supply.Life (Basel, Switzerland) · 2026Article
- Insights in Fetal Growth Trajectories of Spontaneous Twin Anemia Polycythemia Sequence Twins.Fetal diagnosis and therapy · 2026Article
- Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch.Nature biotechnology · 2026Article
- Article
- Prevalence of congenital heart disease in school-aged children and its association with socioeconomic and health service capacity factors: a comparative study of Nepal and China.BMC pediatrics · 2026Article
- Mechanism of FoxO1 in the Metabolic Shift of Fetal Rat Heart.Molecules (Basel, Switzerland) · 2026Article
- Fetal programming of the cardiac mitochondrial permeability transition pore in male offspring from hypoxic pregnancies.Redox biology · 2026Article
- Branched Chain Amino Acid Metabolism in Developmental Brain Injury: Putative Mechanisms and Therapeutic Potential.Developmental neuroscience · 2026Review
- Maternal obesity during pregnancy disrupts iron homeostasis and promotes fetal hypoxia in the mouse.The Journal of physiology · 2026Article
- Article
- Fetal monitoring using a wearable ultrasound patch for high-risk pregnancies.Research square · 2025Article
89 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Until today the role of oxygen in the development of the fetus remains controversially discussed. It is still believed that lack of oxygen in utero might be responsible for some of the known congenital cardiovascular malformations. Over the last two decades detailed research has given us new insights and a better understanding of embryogenesis and fetal growth. But most importantly it has repeatedly demonstrated that oxygen only plays a minor role in the early intrauterine development. After organogenesis has taken place hypoxia becomes more important during the second and third trimester of pregnancy when fetal growth occurs. This review will briefly adress causes and mechanisms leading to intrauterine hypoxia and their impact on the fetal cardiovascular system.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.