ArticleBiomicrofluidics2010
Integrated electrical concentration and lysis of cells in a microfluidic chip.
Article in Biomicrofluidics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Microfluidic Electroporation: Recent Advances and Applications.Advances in experimental medicine and biology · 2026Review
- On Using Electric Circuit Models to Analyze Electric Field Distributions in Insulator-Based Electrokinetically Driven Microfluidic Devices.Micromachines · 2025Article
- Advanced microfluidic systems with temperature modulation for biological applications.Biomicrofluidics · 2025Article
- Optimizing tumor treating fields for blood cancer therapy: Analysis of electric field distribution and dose density.Biophysics and physicobiology · 2024Article
- Manipulation, Sampling and Inactivation of the SARS-CoV-2 Virus Using Nonuniform Electric Fields on Micro-Fabricated Platforms: A Review.Micromachines · 2023Review
- Dynamically controlled dielectrophoresis using resonant tuning.Electrophoresis · 2021Article
- Review of Microfluidic Methods for Cellular Lysis.Micromachines · 2021Review
- Field enhancement in microfluidic semiconductor nanowire array.Biomicrofluidics · 2020Article
- Integrated Electrochemical Biosensors for Detection of Waterborne Pathogens in Low-Resource Settings.Biosensors · 2020Review
- A microchip electrophoresis-mass spectrometric platform with double cell lysis nano-electrodes for automated single cell analysis.Journal of chromatography. A · 2016Article
- Simultaneous diamagnetic and magnetic particle trapping in ferrofluid microflows via a single permanent magnet.Biomicrofluidics · 2015Article
- Viscoelastic effects on electrokinetic particle focusing in a constricted microchannel.Biomicrofluidics · 2015Article
- Fabrication of rigid microstructures with thiol-ene-based soft lithography for continuous-flow cell lysis.Biomicrofluidics · 2014Article
- Microfluidic electroporation for cellular analysis and delivery.Lab on a chip · 2013Review
- Microarray of non-connected gold pads used as high density electric traps for parallelized pairing and fusion of cells.Biomicrofluidics · 2013Article
- Microfluidic separation of live and dead yeast cells using reservoir-based dielectrophoresis.Biomicrofluidics · 2012Article
- Microfluidic concentration of bacteria by on-chip electrophoresis.Biomicrofluidics · 2011Article
- Curvature-induced dielectrophoresis for continuous separation of particles by charge in spiral microchannels.Biomicrofluidics · 2011Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lysing cells is an important step in the analysis of intracellular contents. Concentrating cells is often required in order to acquire adequate cells for lysis. This work presents an integrated concentration and lysis of mammalian cells in a constriction microchannel using dc-biased ac electric fields. By adjusting the dc component, the electrokinetic cell motion can be precisely controlled, leading to an easy switch between concentration and lysis of red blood cells in the channel constriction. These two operations are also used in conjunction to demonstrate a continuous concentration and separation of leukemia cells from red blood cells in the same microchannel. The observed cell behaviors agree reasonably with the simulation results.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.