ArticleGenetics2011
Socially-responsive gene expression in male Drosophila melanogaster is influenced by the sex of the interacting partner.
Article in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Direct and transgenerational effects of tetracyclines on the microbiome, transcriptome, and male mating behavior of the sheep blowfly Lucilia cuprina.G3 (Bethesda, Md.) · 2025Article
- Patterns of Population Structure and Introgression Among Recently Differentiated Drosophila melanogaster Populations.Molecular biology and evolution · 2022Article
- Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila.Life science alliance · 2022Article
- TheFrontiers in neuroscience · 2021Article
- Abnormal Social Interactions in aInternational journal of molecular sciences · 2020Article
- Genetic Basis of Increased Lifespan and Postponed Senescence inG3 (Bethesda, Md.) · 2020Article
- The neuropeptide Drosulfakinin regulates social isolation-induced aggression inThe Journal of experimental biology · 2020Article
- The Role of miRNAs inGenetics · 2019Article
- Conservation of the behavioral and transcriptional response to social experience among Drosophilids.Genes, brain, and behavior · 2019Article
- Mushroom Body Specific Transcriptome Analysis Reveals Dynamic Regulation of Learning and Memory Genes After Acquisition of Long-Term Courtship Memory inG3 (Bethesda, Md.) · 2018Article
- Mating system manipulation and the evolution of sex-biased gene expression in Drosophila.Nature communications · 2017Article
- Socially cued seminal fluid gene expression mediates responses in ejaculate quality to sperm competition risk.Proceedings. Biological sciences · 2017Article
- Genomic responses to the socio-sexual environment in maleRNA (New York, N.Y.) · 2017Article
- Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits.Disease models & mechanisms · 2017Review
- Paternal diet affects differential gene expression, but not sperm competition, in sons.Biology letters · 2017Article
- A Hidden Markov Model Approach for Simultaneously Estimating Local Ancestry and Admixture Time Using Next Generation Sequence Data in Samples of Arbitrary Ploidy.PLoS genetics · 2017Article
- Aggression is associated with aerobic glycolysis in the honey bee brain(1).Genes, brain, and behavior · 2015Article
- Neuromolecular responses to social challenge: common mechanisms across mouse, stickleback fish, and honey bee.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Identification and characterization of seminal fluid proteins in the Asian tiger mosquito, Aedes albopictus.PLoS neglected tropical diseases · 2014Article
- Extensive reorganization of behavior accompanies ontogeny of aggression in male flesh flies.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Behavior is influenced by an organism's genes and environment, including its interactions with same or opposite sex individuals. Drosophila melanogaster perform innate, yet socially modifiable, courtship behaviors that are sex specific and require rapid integration and response to multiple sensory cues. Furthermore, males must recognize and distinguish other males from female courtship objects. It is likely that perception, integration, and response to sex-specific cues is partially mediated by changes in gene expression. Reasoning that social interactions with members of either sex would impact gene expression, we compared expression profiles in heads of males that courted females, males that interacted with other males, or males that did not interact with another fly. Expression of 281 loci changes when males interact with females, whereas 505 changes occur in response to male-male interactions. Of these genes, 265 are responsive to encounters with either sex and 240 respond specifically to male-male interactions. Interestingly, 16 genes change expression only when a male courts a female, suggesting that these changes are a specific response to male-female courtship interactions. We supported our hypothesis that socially-responsive genes can function in behavior by showing that egghead (egh) expression, which increases during social interactions, is required for robust male-to-female courtship. We predict that analyzing additional socially-responsive genes will give us insight into genes and neural signaling pathways that influence reproductive and other behavioral interactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.