Evidence map›Paper›PMID 20979102›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2011

The phage-host arms race: shaping the evolution of microbes.

Adi Stern, Rotem Sorek

Abstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 291 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
291citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

291 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Genomic and functional divergence analysis of closely relatedApplied and environmental microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Bacteriophage-induced outer membrane protein remodelling drives the phenotypic switching and antibiotic re-sensitization in Klebsiella pneumoniae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Isolation and characterization of broad-rangeMicrobiology (Reading, England) · 2026
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Genomic analysis ofVirus evolution · 2026
    Article
  20. Article

231 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adi SternDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Rotem Sorek

Funding

Pan Genomic Discovery of Genes Toxic to BacteriaR01AI082376 · NIAID · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI RUBIN, EDWARD M · 2009 to 2012
$1.6M
NIAID NIH HHS R01 AI082376NIAID NIH HHS R01AI082376-01
6 · The paper itself

Abstract

Bacteria, the most abundant organisms on the planet, are outnumbered by a factor of 10 to 1 by phages that infect them. Faced with the rapid evolution and turnover of phage particles, bacteria have evolved various mechanisms to evade phage infection and killing, leading to an evolutionary arms race. The extensive co-evolution of both phage and host has resulted in considerable diversity on the part of both bacterial and phage defensive and offensive strategies. Here, we discuss the unique and common features of phage resistance mechanisms and their role in global biodiversity. The commonalities between defense mechanisms suggest avenues for the discovery of novel forms of these mechanisms based on their evolutionary traits.

Indexed as

BacteriaBacteriophagesHost-Pathogen InteractionsBiological EvolutionDNA Restriction EnzymesGene Transfer, HorizontalGenomic IslandsMicrobial ViabilityDNA Restriction Enzymes

Identifiers

PMID20979102
PMCPMC3274958

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.