ArticleJournal of plant research2011
An Arabidopsis RNase III-like protein, AtRTL2, cleaves double-stranded RNA in vitro.
Article in Journal of plant research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- The AtRNC1-AtWTF1 protein complex is essential for chloroplast group Ⅱ intron splicing, ribosome biogenesis, and embryo development in Arabidopsis.Plant molecular biology · 2026Article
- Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1.Plant, cell & environment · 2025Article
- The nucleolar protein NOL12 is required for processing of large ribosomal subunit rRNA precursors in Arabidopsis.BMC plant biology · 2023Article
- Soybean antiviral immunity conferred by dsRNase targets the viral replication complex.Nature communications · 2019Article
- Dicer 1 ofVirusdisease · 2019Article
- Regulation of Long Noncoding RNAs Responsive to Phytoplasma Infection inInternational journal of genomics · 2018Article
- Plant dicer-like proteins: double-stranded RNA-cleaving enzymes for small RNA biogenesis.Journal of plant research · 2017Review
- Evolutionary history of double-stranded RNA binding proteins in plants: identification of new cofactors involved in easiRNA biogenesis.Plant molecular biology · 2016Article
- Arabidopsis RNASE THREE LIKE2 Modulates the Expression of Protein-Coding Genes via 24-Nucleotide Small Interfering RNA-Directed DNA Methylation.The Plant cell · 2016Article
- Proteome distribution between nucleoplasm and nucleolus and its relation to ribosome biogenesis in Arabidopsis thaliana.RNA biology · 2016Article
- Plants Encode a General siRNA Suppressor That Is Induced and Suppressed by Viruses.PLoS biology · 2015Article
- ClRTL1 Encodes a Chinese Fir RNase III-Like Protein Involved in Regulating Shoot Branching.International journal of molecular sciences · 2015Article
- A non-canonical RNA silencing pathway promotes mRNA degradation in basal Fungi.PLoS genetics · 2015Article
- Stemming epigenetics in marine stramenopiles.Current genomics · 2011Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Class 1 ribonuclease III (RNase III), found in bacteria and yeast, is involved in processing functional RNA molecules such as ribosomal RNAs (rRNAs). However, in Arabidopsis thaliana, the lack of an obvious phenotype or quantitative change in mature rRNAs in class 1 RNase III (AtRTL2) mutants and overexpressing plants suggests that AtRTL2 is not involved in rRNA maturation. We characterized the in vitro activity of AtRTL2 to consider its in vivo function. AtRTL2 cleaved double-stranded RNA (dsRNA) specifically in vitro, yielding products of approximately 25 nt or longer in length, in contrast to 10-20 nt long products in bacteria and yeasts. Although dsRNA-binding activity was not detected, the dsRNA-binding domains in AtRTL2 were essential for its dsRNA-cleaving activity. Accumulation of small RNAs derived from transgene dsRNAs was increased when AtRTL2 was transiently expressed in Nicotiana benthamiana leaves by agroinfiltration. These results raise the possibility that AtRTL2 has functions distinct from those of other class 1 RNase IIIs in vivo.
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