Trial reportDiabetologia2011
The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes.
Trial report in Diabetologia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 49 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Low Glycemic Index Diets on Glucose Control in Non-Insulin Dependent Diabetics
The Effect of a Low Glycemic Index Diet and Glycemic Load on Body Weight: A Systematic Review and Meta-analyses of Randomized Controlled Trials
Who cites it
49 citing papers in PubMed, 9 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- Low-Glycemic Index Diets as an Intervention in Metabolic Diseases: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Relation of Different Fruit and Vegetable Sources With Incident Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies.Journal of the American Heart Association · 2020Pooled it
- Dietary Glycemic Index and Load and the Risk of Type 2 Diabetes: Assessment of Causal Relations.Nutrients · 2019Pooled it
- Food sources of fructose-containing sugars and glycaemic control: systematic review and meta-analysis of controlled intervention studies.BMJ (Clinical research ed.) · 2018Pooled it
- The Effect of Small Doses of Fructose and Its Epimers on Glycemic Control: A Systematic Review and Meta-Analysis of Controlled Feeding Trials.Nutrients · 2018Pooled it
- Effect of fructose on markers of non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of controlled feeding trials.European journal of clinical nutrition · 2014Pooled it
- Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies.BMJ (Clinical research ed.) · 2013Pooled it
- Associations of glycemic index and load with coronary heart disease events: a systematic review and meta-analysis of prospective cohorts.Journal of the American Heart Association · 2012Pooled it
- 'Catalytic' doses of fructose may benefit glycaemic control without harming cardiometabolic risk factors: a small meta-analysis of randomised controlled feeding trials.The British journal of nutrition · 2012Pooled it
- Short-term effects of goat milk yogurt-containing angiotensin-converting enzyme inhibitory peptides and two raisin varieties on subjective appetite, blood pressure and glycaemic responses in healthy adults. Results from a randomised clinical trial.The British journal of nutrition · 2023Trial
- Both Isocarbohydrate and Hypercarbohydrate Fruit Preloads Curbed Postprandial Glycemic Excursion in Healthy Subjects.Nutrients · 2021Trial
- Apple Preload Halved the Postprandial Glycaemic Response of Rice Meal on in Healthy Subjects.Nutrients · 2019Trial
- Trial
- Fruit form Influences Postprandial Glycemic Response in Elderly and Young Adults.The journal of nutrition, health & aging · 2017Trial
- Greater diet quality is associated with more optimal glycemic control in a longitudinal study of youth with type 1 diabetes.The American journal of clinical nutrition · 2016Trial
- A study of glycemic response to Corinthian raisins in healthy subjects and in type 2 diabetes mellitus patients.Plant foods for human nutrition (Dordrecht, Netherlands) · 2013Trial
- Association Between Fruits and Vegetables Consumption and Premature Coronary Artery Disease (PCAD): A Multi-Center Case Control Study.Food science & nutrition · 2026Article
- Glycemic and Insulinemic Responses of Fresh, Freeze-Dried, and Cooked Apples: As Single Food or Preload.Foods (Basel, Switzerland) · 2025Article
- Article
- Anti-Diabetic Potential of Polyphenol-Rich Fruits from the Maleae Tribe-A Review of In Vitro and In Vivo Animal and Human Trials.Nutrients · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 2 institutions in 2 countries.
Funding
Abstract
aims/hypothesisSugar has been suggested to promote obesity, diabetes and coronary heart disease (CHD), yet fruit, despite containing sugars, may also have a low glycaemic index (GI) and all fruits are generally recommended for good health. We therefore assessed the effect of fruit with special emphasis on low GI fruit intake in type 2 diabetes.
methodsThis secondary analysis involved 152 type 2 diabetic participants treated with glucose-lowering agents who completed either 6 months of high fibre or low GI dietary advice, including fruit advice, in a parallel design.
resultsChange in low GI fruit intake ranged from -3.1 to 2.7 servings/day. The increase in low GI fruit intake significantly predicted reductions in HbA(1c) (r = -0.206, p =0.011), systolic blood pressure (r = -0.183, p = 0.024) and CHD risk (r = -0.213, p = 0.008). Change in total fruit intake ranged from -3.7 to 3.2 servings/day and was not related to study outcomes. In a regression analysis including the eight major carbohydrate foods or classes of foods emphasised in the low GI diet, only low GI fruit and bread contributed independently and significantly to predicting change in HbA(1c). Furthermore, comparing the highest with the lowest quartile of low GI fruit intake, the percentage change in HbA(1c) was reduced by -0.5% HbA(1c) units (95% CI 0.2-0.8 HbA(1c) units, p < 0.001). CONCLUSIONS/
interpretationLow GI fruit consumption as part of a low GI diet was associated with lower HbA(1c), blood pressure and CHD risk and supports a role for low GI fruit consumption in the management of type 2 diabetes.
trial registrationClinicalTrials.gov NCT00438698.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.