Evidence map›Paper›PMID 20978554›Full record

ArticleGastroenterology & hepatology2010

Osteoporosis and gastrointestinal disease.

Seymour Katz, Stuart Weinerman

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Gastroenterology & hepatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07204015 (Body Composition in Pediatric Patients With Thalassemia Major Attending Assiut University Children's Hospital), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07204015 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Body Composition in Pediatric Patients With Thalassemia Major Attending Assiut University Children's Hospital

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled115ConditionsBody Composition in Thalassemia Major
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. The association between irritable bowel syndrome and osteoporosis: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Aging and direct medical costs of osteoporotic fractures.Journal of bone and mineral metabolism · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Bone disease in chronic pancreatitis.World journal of clinical cases · 2020
    Review
  14. Updates on bone health in children with gastrointestinal diseases.Annals of pediatric endocrinology & metabolism · 2020
    Article
  15. Osteocytes and Bone Metastasis.Frontiers in endocrinology · 2020
    Review
  16. Article
  17. Associated Factors for Osteoporosis and Fracture in Chinese Elderly.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Seymour KatzDr. Katz serves as Clinical Professor of Medicine at Albert Einstein College of Medicine in Bronx, New York and as Attending Gastroenterologist at both the North Shore University Hospital-Long Island Jewish Health System in Manhasset, New York and St. Francis Hospital in Roslyn, New York.
Stuart Weinerman
Northwell Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal disease is often overlooked or simply forgotten as a cause of osteoporosis. Yet, the consequences of osteoporotic fractures can be devastating. Although the bulk of the published experience regarding osteoporosis is derived from the postmenopausal population, this review will focus on gastrointestinal disorders implicated in osteoporosis, with an emphasis on inflammatory bowel disease and celiac disease. The unique aspects of gastrointestinal diseases associated with osteoporosis include early onset of disease (and, therefore, prolonged exposure to risk factors for developing osteoporosis, particularly with inflammatory bowel disease and celiac disease), malabsorption, and maldigestion of nutrients necessary for bone health and maintenance (eg, calcium, vitamin D), as well as the impact of glucocorticoids. These factors, when added to smoking, a sedentary lifestyle, hypogonadism, and a family history of osteoporosis, accumulate into an imposing package of predictors for osteoporotic fracture. This paper will review the identification and treatment strategies for patients with gastrointestinal disorders and osteoporosis.

Indexed as

celiac diseaseCrohn's diseasemalabsorptionOsteoporosisRANK/RANKLulcerative colitisvitamin D

Identifiers

PMID20978554
PMCPMC2950667
OpenAlexW1601353500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.