ArticleBritish journal of cancer2010
Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group.
Article in British journal of cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prenatal exposure to medication and risk of childhood cancer - a systematic review and meta-analysis.BMC cancer · 2025Pooled it
- Role of Maternal Diet in the Risk of Childhood Acute Leukemia: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- The Protective Effect of Maternal Folic Acid Supplementation on Childhood Cancer: A Systematic Review and Meta-analysis of Case-control Studies.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2019Pooled it
- Prevention and Health Benefits of Prebiotics, Probiotics and Postbiotics in Acute Lymphoblastic Leukemia.Microorganisms · 2023Review
- Maternal supplementation with folic acid and other vitamins and risk of leukemia in offspring: a Childhood Leukemia International Consortium study.Epidemiology (Cambridge, Mass.) · 2014Article
- Health effects of different dietary iron intakes: a systematic literature review for the 5th Nordic Nutrition Recommendations.Food & nutrition research · 2013Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundPrenatal supplementation has been inversely associated with childhood, but not with infant, leukaemia.
methodsMothers of 443 cases of infant leukaemia diagnosed during 1996-2006 and 324 frequency-matched controls completed interviews. Associations were evaluated by unconditional logistic regression.
resultsWe observed no associations between prenatal vitamin (odds ratio (OR)=0.79, 95% confidence interval (CI): 0.44-1.42) or iron supplementation (OR=1.07, 95% CI: 0.75-1.52) and infant leukaemia after adjustment for race/ethnicity and income. Similar results were observed for leukaemia subtypes analysed separately.
conclusionThe observed null associations may be attributable to high supplementation rates and/or national fortification programmes.
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