ArticleAmerican journal of epidemiology2010
Consanguinity: a risk factor for preterm birth at less than 33 weeks' gestation.
Article in American journal of epidemiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 37 citations in OpenAlex.
- Consanguinity and adverse fetal outcomes- a population-based cohort study from a multiethnic population in the Middle East.BMC pregnancy and childbirth · 2025Article
- Implementation of preconception care for preventing adverse pregnancy outcomes in rural and tribal areas of Nashik District, India.Preventive medicine reports · 2024Article
- Review
- Association between adverse pregnancy outcomes and preceding risk factors: a cross-sectional study from Nashik District, India.BMC pregnancy and childbirth · 2021Article
- Article
- Consanguineous Marriage and the Psychopathology of Progeny: A Population-wide Data Linkage Study.JAMA psychiatry · 2018Observational
- Structural and genomic variation in preterm birth.Pediatric research · 2016Article
- The genetic and environmental factors for keratoconus.BioMed research international · 2015Review
- Re: perinatal mortality rate as a quality indicator of healthcare in Al-dakhiliyah region, oman.Sultan Qaboos University medical journal · 2014Article
- Environmental risk factors and perinatal outcomes in preterm newborns, according to family recurrence of prematurity.American journal of perinatology · 2013Article
- Consanguinity, prematurity, birth weight and pregnancy loss: a prospective cohort study at four primary health center areas of Karnataka, India.Journal of perinatology : official journal of the California Perinatal Association · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Consanguinity promotes homozygosity of recessive susceptibility gene variants and can be used to investigate a recessive component in diseases whose inheritance is uncertain. The objective of this study was to assess the association between consanguinity and preterm birth (PTB), stratified by gestational age and clinical presentation (spontaneous vs. medically indicated). Data were collected on 39,745 singleton livebirths without major birth defects, admitted to 19 hospitals in Lebanon, from September 2003 to December 2007. Deliveries before completed 33 weeks' gestation and deliveries at 33-36 weeks' gestation were compared, with respect to cousin marriage, with those after completed 36 weeks' gestation by using multinomial multiple logistic regression. Overall, infants of consanguineous parents had a statistically significant 1.6-fold net increased risk of being born at less than 33 weeks' gestation compared with infants of unrelated parents. This association was statistically significant only with spontaneous PTB. There was no increased risk of being born at 33-36 weeks' gestation associated with consanguinity for both clinical presentations of PTB. Our findings support a genetic contribution to early onset PTB and suggest that early PTB should be targeted in future genetic studies rather than the classic lumping of all births less than 37 weeks' gestation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.